ARC

Gene Symbol	ARC
Entrez Gene	23237
Alt Symbol	Arg3.1
Species	Human
Gene Type	protein-coding
Description	activity-regulated cytoskeleton-associated protein
Other Description	ARC/ARG3.1|activity-regulated gene 3.1 protein homolog
Swissprots	Q9UJW6 Q9Y469 Q7LC44
Accessions	AAG33705 CBX47608 EAW82320 EAW82321 Q7LC44 AF193421 AAF07185 AI096899 BC012321 AAH12321 BC075802 AAH75802 BI752734 D87468 BAA19667 DQ893666 ABM84592 DQ895780 ABM86706 NM_015193 NP_056008
Function	Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. {ECO:0000250, ECO:0000269|PubMed:21834987}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000250}. Endosome {ECO:0000250|UniProtKB:Q63053, ECO:0000250|UniProtKB:Q9WV31}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q63053, ECO:0000250|UniProtKB:Q9WV31}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail (By similarity). Enriched on the plasma membrane. {ECO:0000250, ECO:0000269|PubMed:21834987}.
Top Pathways	Amphetamine addiction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Arg 3.1 peptide - ab117435 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human Arc full length protein - ab140728 from Abcam Category Protein Prices $297.00 Sizes 10 µg Source E. coli Species Human

Human Arg 3.1 full length protein - ab132919 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Rat Arg 3.1 peptide - ab26899 from Abcam Category Peptide

ARC-Antibody-N-term-Blocking-Peptide - BP14546a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ARC protein (His tag) - 80R-2720 from Fitzgerald Category Protein Prices $270.00 Sizes 10 µg Source E.coli

ARC / ARG3.1 (1-396, His-tag) - AR50840PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 50 µg Source E. coli Species Human

ARC / ARG3.1 (1-396, His-tag) - AR50840PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Source E. coli Species Human

ARC / ARG3.1 - H00023237-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ARC / ARG3.1 - H00023237-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ARC, 1-396aa, Human, His tag, E.coli - 01-P2016 from ARP American Research Products Category Protein Prices $159.00, $369.00, $849.00 Sizes 2 µg, 10 µg, 50 µg Species Human

ARC fusion protein - Ag9445 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ARC, His-tagged - ARC-7572H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human ARC, GST-tagged - ARC-9793H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Activity Regulated Cytoskeleton Associated Protein (ARC) - RPJ620Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Activity Regulated Cytoskeleton Associated Protein (ARC) - RPJ620Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Activity Regulated Cytoskeleton Associated Protein (ARC) - RPJ620Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Activity Regulated Cytoskeleton Associated Protein (ARC) - RPJ620Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Activity Regulated Cytoskeleton Associated Protein (ARC) - RPJ620Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Activity-regulated cytoskeleton-associated protein(ARC) - CSB-YP001981HU CSB-EP001981HU CSB-BP001981HU CSB-MP001981HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ARC, 1-396aa, Human, His tag, E.coli - ATGP2016 from ATGen Category Protein Prices $240.00, $720.00 Sizes 10 µg, 50 µg Species Human

Activity-regulated cytoskeleton-associated protein (Arc) - MBS145591 from MyBioSource Category Protein Prices $140.00, $205.00, $1,220.00 Sizes 1 µg, 5 µg, 50 µg Source E Coli

Actobindin - MBS1474657 from MyBioSource Category Protein Prices $1,870.00, $1,870.00, $2,335.00, $2,335.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ARC / ARG3.1 - TP304129 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ARC, Recombinant Protein - MBS204998 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 10 µg, 50 µg Source E Coli Species Human

Search more