PADI4

Gene Symbol PADI4
Entrez Gene 23569
Alt Symbol PAD, PAD4, PADI5, PDI4, PDI5
Species Human
Gene Type protein-coding
Description peptidyl arginine deiminase, type IV
Other Description HL-60 PAD|PADI-H protein|peptidyl arginine deiminase, type V|protein-arginine deiminase type IV|protein-arginine deiminase type-4
Swissprots B2RBW0 Q70SX4 Q5VTZ8 Q9UM07 A8K392
Accessions CAE47743 CAG30581 CAG30582 CAG30583 CAG30584 CAG30585 CAG30586 CAG30587 CAI84651 EAW94835 EAW94836 Q9UM07 AB017919 BAA84542 AF229067 AAF82265 AK290507 BAF83196 AK309637 AK314839 BAG37357 BC025718 AAH25718 JF432820 ADZ16037 XM_011541150 XP_011539452 XM_011541151 XP_011539453 XM_011541152 XP_011539454 XM_011541153 XP_011539455 XM_011541154 XP_011539456 XM_011541155 XP_011539457 XM_011541156 XP_011539458 XM_011541157 XP_011539459 XM_011548837 XP_011547139 XM_011548838 XP_011547140 XM_011548839 XP_011547141 XM_011548840 XP_011547142 XM_011548841 XP_011547143 XM_011548842 XP_011547144 XM_011548843 XP_011547145 XM_011548844 XP_011547146 NM_012387 NP_036519
Function Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. Citrullinates histone H1 at 'Arg-54' (to form H1R54ci), histone H3 at 'Arg-2', 'Arg-8', 'Arg-17' and/or 'Arg-26' (to form H3R2ci, H3R8ci, H3R17ci, H3R26ci, respectively) and histone H4 at 'Arg-3' (to form H4R3ci). Acts as a key regulator of stem cell maintenance by mediating citrullination of histone H1: citrullination of 'Arg- 54' of histone H1 (H1R54ci) results in H1 displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell maintenance. Promotes profound chromatin decondensation during the innate immune response to infection in neutrophils by mediating formation of H1R54ci. Citrullination of histone H3 prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCO
Subcellular Location Cytoplasm. Nucleus. Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils and neutrophils.
Tissue Specificity Expressed in eosinophils and neutrophils, not expressed in peripheral monocytes or lymphocytes. {ECO:0000269|PubMed:11435484}.

Human PADI4 / PAD4 ELISA Kit (Sandwich ELISA) - LS-F7962 from LifeSpan Bioscience

Category ELISA Kit
Prices $720.00
Sizes 1 plate
Sensitivity 0.313 ng/ml
Range 0.313-20 ng/ml

Human PADI4 ELISA Kit - abx152620 from Abbexa

Category ELISA Kit
Sensitivity 0.115 ng/ml
Range 0.031 ng/ml - 2 ng/ml

Peptidyl Arginine Deiminase Type IV, PADI4, Human, ELISA Kit - E-EL-H1322 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 0.113
Range 0.188-12ng/mL

Protein-arginine deiminase type-4 (PADI4) antibody, Human, ELISA Kit - CSB-E13109h from ARP American Research Products

Category ELISA Kit
Prices $550.00, $790.00, $791.00, $794.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Peptidyl Arginine Deiminase Type IV, PADI4, Rabbit, ELISA Kit - E-EL-RB0177 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Peptidyl Arginine Deiminase Type IV, PADI4, Chicken, ELISA Kit - E-EL-Ch0608 from ARP American Research Products

Category ELISA Kit
Prices $504.00
Sizes 96 t

Peptidyl Arginine Deiminase Type IV, PADI4, Porcine, ELISA Kit - E-EL-P1541 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Peptidyl Arginine Deiminase Type IV, PADI4, Monkey, ELISA Kit - E-EL-MK0691 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Human PADI4(Peptidyl Arginine Deiminase Type Ⅳ) ELISA Kit - E-EL-H1322 from Elabscience

Category ELISA Kit
Sensitivity 0.11 ng/mL
Range 0.19—12 ng/mL

Human PADI4 (Peptidyl Arginine Deiminase Type IV) CLIA Kit - E-CL-H0866 from Elabscience

Category CLIA Kit
Sensitivity 37.50 pg/mL
Range Average Recovery (%)

PADI4, ELISA Kit - MBS2504967 from MyBioSource

Category ELISA Kit
Prices $450.00, $535.00, $2,255.00, $3,975.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.094ng/mL
Range 0.156-10ng/mL

PADI4, ELISA Kit - MBS2513766 from MyBioSource

Category ELISA Kit
Prices $450.00, $535.00, $2,255.00, $3,975.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.113ng/mL
Range 0.188-12ng/mL

PADI4, ELISA Kit - MBS2505910 from MyBioSource

Category ELISA Kit
Prices $410.00, $490.00, $2,040.00, $3,590.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.113ng/mL
Range 0.188-12ng/mL

PADI4, ELISA Kit - MBS2503620 from MyBioSource

Category ELISA Kit
Prices $450.00, $535.00, $2,255.00, $3,975.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.113ng/mL
Range 0.188-12ng/mL

PADI4, ELISA Kit - MBS2507726 from MyBioSource

Category ELISA Kit
Prices $450.00, $535.00, $2,255.00, $3,975.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 75pg/mL
Range 125-8000pg/mL

Peptidyl Arginine Deiminase Type IV (PADI4), ELISA Kit - MBS2021866 from MyBioSource

Category ELISA Kit
Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity <0.135ng/mL
Range 0.312-20ng/mL

peptidyl arginine deiminase, type IV, ELISA Kit - MBS706202 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.039 ng/ml
Range 0.156 ng/ml-10 ng/ml.

Protein-arginine deiminase type-4, ELISA Kit - MBS281113 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein-arginine deiminase type-4 - MBS281051 from MyBioSource

Category ELISA Kit
Prices $930.00
Sizes 96 tests

Protein-arginine deiminase type-4 (PADI4) antibody, ELISA Kit - MBS702910 from MyBioSource

Category ELISA Kit
Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Peptidyl Arginine Deiminase Type IV (PADI4) - SEF709Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.137ng/mL.
Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human PADI4 (Peptidyl Arginine Deiminase Type IV) CLIA Kit - E-CL-H0866 from Iwai North America Inc.

Category CLIA Kit
Prices $722.50
Sizes 1 kit
Sensitivity 0.113ng/mL
Range 0.188-12ng/mL

Human PADI4 / PAD4 ELISA Kit (Sandwich ELISA) - LS-F21746 from LifeSpan Bioscience

Category ELISA Kit
Prices $590.00
Sizes 1 plate
Sensitivity 0.19 ng/ml
Range 0.313-20 ng/ml

Peptidyl Arginine Deiminase Type IV (PADI4), Human, ELISA Kit - DL-PADI4-Hu from ARP American Research Products

Category ELISA Kit
Prices $655.00
Sizes 96 t
Range 0.188-12 ng/mL
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