CYR61

Gene Symbol	CYR61
Entrez Gene	3491
Alt Symbol	CCN1, GIG1, IGFBP10
Species	Human
Gene Type	protein-coding
Description	cysteine-rich, angiogenic inducer, 61
Other Description	CCN family member 1|IBP-10|IGF-binding protein 10|IGFBP-10|cysteine-rich heparin-binding protein 61|cysteine-rich, anigogenic inducer, 61|insulin-like growth factor-binding protein 10|protein CYR61
Swissprots	O43775 Q9BZL7 O14934 O00622
Accessions	AAG59863 AAR05446 EAW73196 EAW73197 EAW73198 O00622 AF003114 AAF21597 AF003594 AAB61240 AF031385 AAB84227 AK096420 AK223385 BAD97105 AK295430 BAG58373 AK314571 BAG37152 AL832891 BC001271 AAH01271 BC009199 AAH09199 BC016952 AAH16952 BP387218 CR536519 CAG38757 DA764894 DQ891262 ABM82188 DQ894449 ABM85375 U62015 AAB58319 Y11307 CAA72167 Y12084 CAA72802 Z50168 Z97068 CAB09804 Z98053 CAB10848 NM_001554 NP_001545
Function	Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up- regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3. {ECO:0000269|PubMed:11584015}.
Subcellular Location	Secreted.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CYR61 ELISA Kit (Sandwich ELISA) - LS-F2883 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 31.2 pg/ml Range 31.2-2000 pg/ml

Human CYR61 ELISA Kit (Sandwich ELISA) - LS-F7063 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 27.2 pg/ml Range 31.2-2000 pg/ml

Mouse CYR61 ELISA Kit (Sandwich ELISA) - LS-F8609 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 6.25 pg/ml Range 31.2-2000 pg/ml

Human CYR61 ELISA Kit (Sandwich ELISA) - LS-F11268 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 31.2 Range 31.2-2000 pg/ml

Human Cyr61/CCN1 DuoSet ELISA - DY4055 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 31.20 - 2,000 pg/mL

Human Cyr61/CCN1 Quantikine ELISA Kit - DCYR10 from R&D Systems Category ELISA Kit Prices $519.00 Sizes 1 kit Sensitivity 3.8 pg/mL Range 39.1 - 2,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Saliva, Human Milk)

Quantikine Immunoassay Control Set 786 for Human Cyr61/CCN1 - QC73 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Human CYR61 ELISA Kit - abx056132 from Abbexa Category ELISA Kit

Human CYR61 ELISA Kit - abx151229 from Abbexa Category ELISA Kit Sensitivity 0.141 ng/ml Range 0.313 ng/ml - 20 ng/ml

Cysteine Rich Protein, Angiogenic Inducer 61, Cyr61, Human, ELISA Kit - E-EL-H1285 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61), Human, ELISA Kit - SEG313Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 13.4pg/mL Range 31.2-2,000pg/mL

Cysteine-rich 61 (Cyr61/CCN1), Human, ELISA Kit - CSB-E13884h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.2 ng/ml Range 0.78 ng/ml-50 ng/ml

Protein CYR61, CYR61, Human, ELISA Kit - E0494h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 31.2-2000 pg/mL

Cysteine Rich Protein, Angiogenic Inducer 61, Cyr61, Rabbit, ELISA Kit - E-EL-RB0451 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Cysteine Rich Protein, Angiogenic Inducer 61, Cyr61, Chicken, ELISA Kit - E-EL-Ch0328 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Cysteine Rich Protein, Angiogenic Inducer 61, Cyr61, Porcine, ELISA Kit - E-EL-P2166 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Cysteine Rich Protein, Angiogenic Inducer 61, Cyr61, Monkey, ELISA Kit - E-EL-MK0132 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Cyr61, ELISA Kit - MBS2515572 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.75pg/mL Range 1.25-80pg/mL

Cyr61, ELISA Kit - MBS2502791 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

CYR61, ELISA Kit - MBS824971 from MyBioSource Category ELISA Kit Prices $470.00 Sizes 96 tests Sensitivity 10 pg/ml Range 31.2 pg/ml - 2000 pg/ml

Cyr61, ELISA Kit - MBS2506154 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

Cyr61, ELISA Kit - MBS2505419 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938pg/mL Range 1.563-100pg/mL

Cyr61, ELISA Kit - MBS2510311 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25--2000pg/mL

CYR61 Cysteine-rich protein 61, Cyr 61, ELISA Kit - MBS9304223 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CYR61/CCN1, ELISA Kit - MBS177255 from MyBioSource Category ELISA Kit Prices $425.00 Sizes 1x96 wells Sensitivity < 10pg/ml Range 31.2pg/ml-2000pg/ml

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