RNF43

Gene Symbol	RNF43
Entrez Gene	54894
Alt Symbol	RNF124, URCC
Species	Human
Gene Type	protein-coding
Description	ring finger protein 43
Other Description	E3 ubiquitin-protein ligase RNF43
Swissprots	B7Z5D5 Q68DV7 B7Z443 B7Z5J5 Q65ZA4 Q6AI04 Q9NXD0 A8K4R2
Accessions	EAW94458 EAW94459 Q68DV7 AB081837 BAD51435 AK000322 BAA91085 AK291027 BAF83716 AK296769 BAH12429 AK298789 BAH12871 AK299024 BAH12931 AK309297 BC109028 AAI09029 CR627423 CAH10510 CR749257 CAH18113 DA457410 DA723235 XM_011524954 XP_011523256 XM_011524955 XP_011523257 XM_011524956 XP_011523258 NM_001305544 NP_001292473 NM_001305545 NP_001292474 NM_017763 NP_060233
Function	E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. {ECO:0000269|PubMed:18313049, ECO:0000269|PubMed:22575959, ECO:0000269|PubMed:22895187}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus envelope. Note=According to a report, may be secreted. {ECO:0000269|PubMed:15492824}.
Tissue Specificity	Expressed in fetal kidney, fetal lung, in colon cancer tissues, hepatocellular carcinomas and lung adenocarcinomas. Overexpressed in colorectal cancer cell lines. {ECO:0000269|PubMed:15492824, ECO:0000269|PubMed:18313049}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RNF43 (G-15) - sc-165396 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

RNF43 (P-16) - sc-165397 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

RNF43 (S-16) - sc-165398 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-RNF43 antibody - ab84125 from Abcam Prices $376.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-RNF43 antibody - ab129401 from Abcam Prices $376.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-RNF43 Antibody (aa504-553) - LS-C102008 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-RNF43 Antibody (aa543-572) - LS-C162663 from LifeSpan Bioscience Host Rabbit Clonality Polyclonal

Anti-RNF43 Antibody (aa542-572, APC) - LS-C207582 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RNF43 Antibody (aa542-572, Biotin) - LS-C207583 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RNF43 Antibody (aa542-572, FITC) - LS-C207584 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RNF43 Antibody (aa542-572, AP) - LS-C207581 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RNF43 Antibody (aa542-572, PE) - LS-C207585 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RNF43 Antibody (aa542-572, Azide-free, HRP) - LS-C207587 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RNF43 Antibody (aa542-572) - LS-C324747 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

RNF43 Antibody - NBP1-85018 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RNF43 Antibody - NBP1-69499 from Novus Biologicals Prices $329.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

RNF43 Polyclonal Antibody - bs-7007R from Bioss Prices $269.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RNF43 antibody produced in rabbit - SAB2102033 from Sigma-Aldrich Prices $347.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RNF43 antibody produced in rabbit - HPA008079 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RNF43 antibody - middle region (ARP43227_P050) - ARP43227_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RNF43-Antibody-C-term - AP13204b from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

RNF43 Antibody - C-terminal region (OAAB09509) - OAAB09509 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

RNF43 Antibody (OABF01771) - OABF01771 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RNF43 antibody - 70R-7336 from Fitzgerald Prices $345.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

RNF43 Antibody - 25-834 from ProSci Prices $315.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

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