EPCAM

Gene Symbol EPCAM
Entrez Gene 4072
Alt Symbol DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1
Species Human
Gene Type protein-coding
Description epithelial cell adhesion molecule
Other Description adenocarcinoma-associated antigen|cell surface glycoprotein Trop-1|epithelial glycoprotein 314|human epithelial glycoprotein-2|major gastrointestinal tumor-associated protein GA733-2|membrane component, chromosome 4, surface marker (35kD glycoprotein)|tumor-associated calcium signal transducer 1
Swissprots P16422 Q9UCD0 Q6FG49 Q96C47 Q6FG26 P18180
Accessions AAB00775 AAY15095 CAG28087 EAX00218 EAX00219 P16422 AK026585 AW050533 BC014785 AAH14785 BP262680 CR542259 CAG47055 CR542283 CAG47078 DA963872 DB044092 DQ891338 ABM82264 DQ894520 ABM85446 M26481 AAA59543 M32306 AAA35723 M32325 AAA36151 M33011 AAA35861 X14758 CAA32870 NM_002354 NP_002345
Function May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. {ECO:0000269|PubMed:15195135, ECO:0000269|PubMed:15922867, ECO:0000269|PubMed:19785009, ECO:0000269|PubMed:20064925}.
Subcellular Location Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction.
Tissue Specificity Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. {ECO:0000269|PubMed:20064925}.

EpCAM (VU1D9) Mouse mAb (Pacific Blue™ Conjugate) - 9032 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Mouse
Clonality Monoclonal
Clone VU1D9
Flow cytometric analysis of unpermeabilized HT-29 cells using EpCAM (VU1D9) Mouse mAb (Pacific Blue™ Conjugate) (green) compared to a nonspecific negative control antibody (red).

EpCAM (VU1D9) Mouse mAb (PE Conjugate) - 8995 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Mouse
Clonality Monoclonal
Clone VU1D9
Flow cytometric analysis of unpermeablized HT-29 cells using EpCAM (VU1D9) Mouse mAb (PE Conjugate) (green) compared to concentration-matched Mouse (G3A1) mAb IgG1 Isotype Control (PE Conjugate) #6899 (red).

EpCAM (VU1D9) Mouse mAb (Alexa Fluor ® 488 Conjugate) - 5198 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Mouse
Clonality Monoclonal
Clone VU1D9
Confocal immunofluorescent analysis of HT-29 cells using EpCAM (VU1D9) Mouse mAb (Alexa Fluor® 488 Conjugate) (green). Actin filaments were labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).

EpCAM (VU1D9) Mouse mAb (Alexa Fluor ® 594 Conjugate) - 7319 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Mouse
Clonality Monoclonal
Clone VU1D9
Confocal immunofluorescent analysis of HT-29 (left) and HeLa (right) cells using EpCAM (VU1D9) Mouse mAb (Alexa Fluor ® 594 Conjugate) (red). Actin filaments were labeled with Alexa Fluor ® 488 phalloidin (green). Blue pseudocolor = DRAQ5 ® #4084 (fluorescent DNA dye).

EpCAM (VU1D9) Mouse mAb (Alexa Fluor ® 555 Conjugate) - 5488 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Mouse
Clonality Monoclonal
Clone VU1D9
Confocal immunofluorescent analysis of HT-29 cells (left) and HeLa cells (right) using EpCAM (VU1D9) Mouse mAb (Alexa Fluor ® 555 Conjugate) (red). Blue pseudocolor= DRAQ5 ® #4084 (fluorescent DNA dye).

EpCAM (VU1D9) Mouse mAb (Alexa Fluor ® 647 Conjugate) - 5447 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Mouse
Clonality Monoclonal
Clone VU1D9
Confocal immunofluorescent analysis of HT-29 cells using EpCAM (VU1D9) Mouse mAb (Alexa Fluor® 647 Conjugate) (blue pseudocolor) and Di-Methyl-Histone H3 (Lys4) (C64G9) Rabbit mAb #9725 (green).

EpCAM (D1B3) Rabbit mAb - 2626 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D1B3
Western blot analysis of extracts from MCF7 (EpCAM positive), HT-29 (EpCAM positive), and HeLa (EpCAM negative) cells using EpCAM (D1B3) Rabbit mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower).

EpCAM (VU1D9) Mouse mAb - 2929 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone VU1D9
Western blot analysis of extracts from HT-29 and HCT-15 cells using EpCAM (VU1D9) Mouse mAb.

EpCAM (D9S3P) Rabbit mAb (IHC Preferred) - 14452 from Cell Signaling Technology

Prices $250.00
Sizes 100 µl (200 sections)
Host Rabbit
Clonality Monoclonal
Clone D9S3P
Western blot analysis of extracts from MCF7 (EpCAM positive), HT-29 (EpCAM positive), and HeLa (EpCAM negative) cells using EpCAM (D9S3P) Rabbit mAb (IHC Preferred) (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).

EpCAM Antibody - 3599 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HT-29, HCT-15 and HCT-116 cells using EpCAM Antibody.

CA215 (RP 215) - sc-69849 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Ep-CAM (C-10) - sc-25308 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (C-10) PE: sc-25308 PE. FCM analysis of SW480 cells. Black line histogram represents the isotype control, normal mouse IgG<sub>2a</sub>: sc-2867.

Ep-CAM (A-20) - sc-23788 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ep-CAM (A-20): sc-23788. Western blot analysis of Ep-CAM expression in MCF7 whole cell lysate.

Ep-CAM (H-70) - sc-20154 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Ep-CAM (H-70): sc-20154. Western blot analysis of Ep-CAM expression in non-transfected 293T: sc-117752 (A), human Ep-CAM transfected 293T: sc-113013 (B) and A-431 (C) whole cell lysates.

Ep-CAM (9C4) - sc-21792 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (9C4) PE: sc-21792 PE. FCM analysis of SW480 cells. Black line histogram represents the isotype control, normal mouse IgG2b, sc-2868.

Ep-CAM (KS1/4) - sc-33687 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (KS1/4) PE: sc-33687 PE. FCM analysis of SW480 cells. Black line histogram represents the isotype control, normal mouse IgG<sub>2a</sub>: sc-2867.

Ep-CAM (EBA-1) - sc-66020 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (EBA-1): sc-66020. Western blot analysis of Ep-CAM expression in MCF7 whole cell lysate.

Ep-CAM (VU-1D9) - sc-51681 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (VU-1D9): sc-51681. Western blot analysis of Ep-CAM expression in non-transfected 293T: sc-117752 (A), human Ep-CAM transfected 293T: sc-113013 (B) and A-431 (C) whole cell lysates.

Ep-CAM (AUA1) - sc-53277 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (AUA1): sc-53277. Western blot analysis of Ep-CAM expression in Ca Ski (A), Caco-2 (B), LS1034 (C) and SHP-77 (D) whole cell lysates and human prostate tumor tissue extract (E).

Ep-CAM (HEA125) - sc-59906 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (HEA125): sc-59906. Western blot analysis of Ep-CAM expression in MCF7 (A), A-431 (B), Ca Ski (C), Caco-2 (D), LS1034 (E), SHP-77 (F) and Hep G2 (G) whole cell lysates under non-reducing conditions.

Ep-CAM (323/A3) - sc-73491 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (323/A3): sc-73491. Western blot analysis of Ep-CAM expression in non-transfected: sc-117752 (A) and human Ep-CAM transfected: sc-113013 (B) 293T whole cell lysates.

Ep-CAM (B302) - sc-59783 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (B302): sc-59783. Western blot analysis of Ep-CAM expression in non-transfected: sc-117752 (A) and human Ep-CAM transfected: sc-113013 (B) 293T whole cell lysates.

Ep-CAM (0.N.276) - sc-71059 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (0.N.276): sc-71059. Western blot analysis of Ep-CAM expression in non-transfected: sc-117752 (A) and human Ep-CAM transfected: sc-113013 (B) 293T whole cell lysates.

Ep-CAM (5F209) - sc-71057 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (5F209): sc-71057. Western blot analysis of Ep-CAM expression in MCF7 whole cell lysate.

Ep-CAM (3H2141) - sc-71056 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ep-CAM (3H2141): sc-71056. Western blot analysis of Ep-CAM expression in MCF7 whole cell lysate.
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