EPCAM

Gene Symbol	EPCAM
Entrez Gene	4072
Alt Symbol	DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1
Species	Human
Gene Type	protein-coding
Description	epithelial cell adhesion molecule
Other Description	adenocarcinoma-associated antigen|cell surface glycoprotein Trop-1|epithelial glycoprotein 314|human epithelial glycoprotein-2|major gastrointestinal tumor-associated protein GA733-2|membrane component, chromosome 4, surface marker (35kD glycoprotein)|tumor-associated calcium signal transducer 1
Swissprots	P16422 Q9UCD0 Q6FG49 Q96C47 Q6FG26 P18180
Accessions	AAB00775 AAY15095 CAG28087 EAX00218 EAX00219 P16422 AK026585 AW050533 BC014785 AAH14785 BP262680 CR542259 CAG47055 CR542283 CAG47078 DA963872 DB044092 DQ891338 ABM82264 DQ894520 ABM85446 M26481 AAA59543 M32306 AAA35723 M32325 AAA36151 M33011 AAA35861 X14758 CAA32870 NM_002354 NP_002345
Function	May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. {ECO:0000269|PubMed:15195135, ECO:0000269|PubMed:15922867, ECO:0000269|PubMed:19785009, ECO:0000269|PubMed:20064925}.
Subcellular Location	Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction.
Tissue Specificity	Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. {ECO:0000269|PubMed:20064925}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human EpCAM protein fragment - ab155712 from Abcam Category Protein Prices $352.00 Sizes 100 µg Source HEK 293 cells Species Human

Active human EpCAM protein fragment - ab155637 from Abcam Category Protein Prices $352.00 Sizes 100 µg Source HEK 293 cells Species Human

Human EpCAM full length protein - ab131790 from Abcam Category Protein Source Wheat germ Species Human

Human EpCAM peptide - ab71914 from Abcam Category Peptide

Human EpCAM peptide - ab71915 from Abcam Category Peptide

Human EpCAM protein fragment - ab139217 from Abcam Category Protein Source E. coli Species Human

Human EpCAM protein fragment - ab151338 from Abcam Category Protein Source HEK 293 cells Species Human

Human EpCAM protein fragment - ab190417 from Abcam Category Protein Source E. coli Species Human

Recombinant Human EpCAM/TROP1 Protein - H00004072-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human EpCAM/TROP1 Protein - NBP2-23025 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

Recombinant Human EpCAM/TROP1 Protein - H00004072-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

EpCAM-Antibody-C-term-Blocking-Peptide - BP18115b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

EpCAM-Antibody-N-term-Blocking-peptide - BP5443a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human EpCAM/TROP1 Fc Chimera, CF - 960-EP-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Epithelial Cell Extract Protein (OPMA04148) - OPMA04148 from Aviva Systems Biology Category Protein Prices $110.00 Sizes 1 ml Source Human whole cell culture

Human EpCAM protein - orb49363 from Biorbyt Category Protein Prices $238.00, $476.00, $2,321.00, $3,281.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human Epithelial Cell Adhesion Molecule protein - orb82981 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Cynomolgus Epithelial Cell Adhesion Molecule protein - orb138767 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells

Human EpCAM protein - orb168304 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human Epithelial Cell Adhesion Molecule protein - orb83529 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Cynomolgus Epithelial Cell Adhesion Molecule protein - orb138768 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells

EpCAM peptide - orb72649 from Biorbyt Category Peptide Prices $238.00 Sizes 500 µg

EPCAM protein (His tag) - 30R-2909 from Fitzgerald Category Protein Prices $295.00 Sizes 100 µg Source E.coli

CD326 / EPCAM / TACSTD1 (24-265, His-tag) - AR50669PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CD326 / EPCAM / TACSTD1 (24-265, His-tag) - AR50669PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

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