EPCAM

Gene Symbol	EPCAM
Entrez Gene	4072
Alt Symbol	DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1
Species	Human
Gene Type	protein-coding
Description	epithelial cell adhesion molecule
Other Description	adenocarcinoma-associated antigen|cell surface glycoprotein Trop-1|epithelial glycoprotein 314|human epithelial glycoprotein-2|major gastrointestinal tumor-associated protein GA733-2|membrane component, chromosome 4, surface marker (35kD glycoprotein)|tumor-associated calcium signal transducer 1
Swissprots	P16422 Q9UCD0 Q6FG49 Q96C47 Q6FG26 P18180
Accessions	AAB00775 AAY15095 CAG28087 EAX00218 EAX00219 P16422 AK026585 AW050533 BC014785 AAH14785 BP262680 CR542259 CAG47055 CR542283 CAG47078 DA963872 DB044092 DQ891338 ABM82264 DQ894520 ABM85446 M26481 AAA59543 M32306 AAA35723 M32325 AAA36151 M33011 AAA35861 X14758 CAA32870 NM_002354 NP_002345
Function	May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. {ECO:0000269|PubMed:15195135, ECO:0000269|PubMed:15922867, ECO:0000269|PubMed:19785009, ECO:0000269|PubMed:20064925}.
Subcellular Location	Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction.
Tissue Specificity	Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. {ECO:0000269|PubMed:20064925}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TACSTD1-Over-expression-Lysate - LY12813a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

TACSTD1 293T Cell Transient Overexpression Lysate(Denatured) - H00004072-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

TACSTD1 293T Cell Transient Overexpression Lysate(Denatured) - H00004072-T02 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

EPCAM overexpression lysate - LY400847 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

EPCAM 293 Cell Lysate - 400806 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

EpCAM/TROP1 Overexpression Lysate (Denatured) - H00004072-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

EpCAM/TROP1 Overexpression Lysate (Denatured) - H00004072-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

Ep-CAM (h): 293T Lysate - sc-159303 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Ep-CAM (h2): 293T Lysate - sc-159491 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Ep-CAM (h3): 293T Lysate - sc-113013 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

EPCAM Over-expression Lysate Product - GWB-65F3E3 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Cynomolgus / Rhesus EpCAM / TROP-1 / TACSTD1 HEK293 Cell Lysate (WB positive control) - 90299-CCCHL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Cynomolgus EpCAM / TROP-1 / TACSTD1 HEK293 Cell Lysate (WB positive control) - 90299-C08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Cynomolgus / Rhesus EpCAM / TROP-1 / TACSTD1 HEK293 Cell Lysate (WB positive control) - 90299-C02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Human EpCAM / TROP-1 / TACSTD1 HEK293 Cell Lysate (WB positive control) - 10694-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human EpCAM / TROP-1 / TACSTD1 HEK293 Cell Lysate (WB positive control) - 10694-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Panoply™ Human EPCAM Knockdown Stable Cell Line - CSC-DC004980 from Creative biogene Category Cell Line Species Human

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