IFNL1

Gene Symbol	IFNL1
Entrez Gene	282618
Alt Symbol	IL-29, IL29
Species	Human
Gene Type	protein-coding
Description	interferon, lambda 1
Other Description	IFN-lambda-1|cytokine Zcyto21|interferon lambda-1|interferon-lambda-1|interleukin 29 (interferon, lambda 1)|interleukin-29
Swissprots	Q17R34 A0AV25 Q8IU54
Accessions	CAI75183 CAJ41836 CAL33802 CAL68893 CAL68894 CAS97664 CAT00937 CAT00938 CAT02302 CBI85489 CBI85490 CBY45348 CBY45408 CDL78891 EAW56871 Q8IU54 AY129150 AAN28265 AY184372 AAN86125 AY336716 AAR24511 BC074985 AAH74985 BC117482 AAI17483 BC126183 AAI26184 HQ214053 ADO12077 HQ258085 ADR82839 JF268782 AEV89427 NM_172140 NP_742152
Function	Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN- stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type- selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Subcellular Location	Secreted.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IL-29 (Interleukin-29) Human ELISA Kit - ab100568 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 20 pg/ml Range 13.72 pg/ml - 10000 pg/ml

Human IFNL1 / IL29 ELISA Kit (Sandwich ELISA) - LS-F2792 from LifeSpan Bioscience Category ELISA Kit Prices $490.00 Sizes 1 plate Sensitivity 10 pg/ml Range 13.72-10000 pg/ml

Human IFNL1 / IL29 ELISA Kit (Sandwich ELISA) - LS-F4456 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 2.7 pg/ml Range 13.72-10000 pg/ml

Human IFNL1 / IL29 ELISA Kit (Sandwich ELISA) - LS-F124 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 13.72 pg/ml Range 13.72-10000 pg/ml

Human IFNL1 / Interferon lambda-1 ELISA Kit - RAB0293 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human IL-29/IL-28B (IFN-lambda 1/3) DuoSet ELISA - DY1598B from R&D Systems Category ELISA Kit Prices $249.00, $649.00 Sizes 1 kit (for 5 Plates), 1 kit (for 15 Plates) Range 62.50 - 4,000 pg/mL

Human IL-29/IFN-lambda 1 DuoSet ELISA - DY7246 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 62.50 - 4,000 pg/mL

Human IL-29/IL-28B (IFN-lambda 1/3) DuoSet, 5 Plate - DY1598B-05 from R&D Systems Category ELISA Kit

Human IL-29 ELISA Kit - abx056230 from Abbexa Category ELISA Kit

Interleukin 29 (IL-29), Human, ELISA Kit - CSB-E14290h from ARP American Research Products Category ELISA Kit Prices $450.00, $595.00, $596.00, $599.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Interleukin 29 (IL29), Human, ELISA Kit - SEC029Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 6.6pg/mL Range 15.6-1,000pg/mL

Interleukin-29, IL29, Human, ELISA Kit - E2029h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 15.6-1000 pg/mL

Interleukin 29 (IL29), Human, CLIA Kit - SCC029Hu from ARP American Research Products Category CLIA Kit Prices $840.00 Sizes 96 t Sensitivity 4.5pg/mL Range 15.6-1,000pg/mL

IL29 (Human) ELISA Kit - KA0997 from Acris Antibodies Category ELISA Kit Prices $650.00 Sizes 1 kit

Human IL-29 ELISA - ELH-IL29 from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,561.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 20 pg/ml Range 20 pg/ml - 10000 pg/ml

LEGEND MAX™ Human IL-29 ELISA Kit with Pre-coated Plates - 435607 from Biolegend Category ELISA Kit Prices $395.00, $1,395.00 Sizes 1 pre-coated plate, 5 pre-coated plates Sensitivity 17.7 pg/mL Range 62.5-4,000 pg/mL

IL-29, ELISA Kit - MBS824865 from MyBioSource Category ELISA Kit Prices $470.00 Sizes 96 tests Sensitivity 10 pg/ml Range 62.5 pg/ml - 4000 pg/ml

IL-29, ELISA Kit - MBS2516330 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

IL-29 - MBS494982 from MyBioSource Category ELISA Kit Sensitivity < 10pg/ml Range 62.5pg/ml-4000pg/ml

IL-29, ELISA Kit - MBS177142 from MyBioSource Category ELISA Kit Prices $390.00 Sizes 1x96 wells Sensitivity < 10pg/ml Range 62.5pg/ml-4000pg/ml

Human IL-29 / IFN-lambda 1 ELISA Kit - DEIA5561 from Creative Diagnostics Category ELISA Kit Sensitivity 20 pg/mL

Human IL-29(Interleukin 29) ELISA Kit - E-EL-H5509 from Elabscience Category ELISA Kit Sensitivity 9.38 pg/mL Range 15.63—1000 pg/mL

Interleukin 29, ELISA Kit - MBS043274 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 29, ELISA Kit - MBS043283 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 29, ELISA Kit - MBS748056 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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