IFNL1

Gene Symbol IFNL1
Entrez Gene 282618
Alt Symbol IL-29, IL29
Species Human
Gene Type protein-coding
Description interferon, lambda 1
Other Description IFN-lambda-1|cytokine Zcyto21|interferon lambda-1|interferon-lambda-1|interleukin 29 (interferon, lambda 1)|interleukin-29
Swissprots Q17R34 A0AV25 Q8IU54
Accessions CAI75183 CAJ41836 CAL33802 CAL68893 CAL68894 CAS97664 CAT00937 CAT00938 CAT02302 CBI85489 CBI85490 CBY45348 CBY45408 CDL78891 EAW56871 Q8IU54 AY129150 AAN28265 AY184372 AAN86125 AY336716 AAR24511 BC074985 AAH74985 BC117482 AAI17483 BC126183 AAI26184 HQ214053 ADO12077 HQ258085 ADR82839 JF268782 AEV89427 NM_172140 NP_742152
Function Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN- stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type- selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Subcellular Location Secreted.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Human-IL29-cDNA-Clone - DC14355 from Abgent, a WuXi AppTec company

Prices $270.00
Sizes 10 µg
Species Human
Accession BC074985

IL29 - MBS1272200 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC117482

IL29 - MBS1273067 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC126183

Human IL29 cDNA clone(NM_172140.1) - CDFG010433 from Creative Biomart

Species Human
Accession NM_172140.1

Human IL29 ORF Clone(NM_172140.1) - CDCR321254 from Creative Biomart

Species Human
Accession NM_172140.1

Human IL29 ORF Clone(NM_172140.1) - CDCR321255 from Creative Biomart

Species Human
Accession NM_172140.1

Human IL29 ORF Clone(NM_172140.1) - CDCR321256 from Creative Biomart

Species Human
Accession NM_172140.1

Human IL29 ORF Clone(NM_172140.1) - CDCR321256 from Creative biogene

Species Human

Human IL29 ORF Clone (BC117482) - CDCS417365 from Creative biogene

Species Human
Accession Q8IU54

Human IL29 ORF Clone (BC126183) - CDCS417366 from Creative biogene

Species Human
Accession Q8IU54

Human IL29 cDNA Clone(NM_172140.1) - CDFG010433 from Creative biogene

Species Human
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