| Gene Symbol | SNRPA |
|---|---|
| Entrez Gene | 6626 |
| Alt Symbol | Mud1, U1-A, U1A |
| Species | Human |
| Gene Type | protein-coding |
| Description | small nuclear ribonucleoprotein polypeptide A |
| Other Description | U1 small nuclear RNP-specific A|U1 small nuclear ribonucleoprotein A|U1 snRNP A|U1 snRNP-specific protein A |
| Swissprots | P09012 |
| Accessions | AAA61245 EAW56995 EAW56996 P09012 AK293140 BAG56688 AK313182 BAG35999 BC000405 AAH00405 BC008290 AAH08290 BQ002918 CN286572 X06347 CAA29653 NM_004596 NP_004587 |
| Function | Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs. {ECO:0000269|PubMed:9848648}. |
| Subcellular Location | Nucleus. |
| Top Pathways | Spliceosome |
SNRPA (Human) Matched Antibody Pair - H00006626-AP11 from Acris Antibodies
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SNRPA (Human) Matched Antibody Pair - H00006626-AP21 from Acris Antibodies
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small nuclear ribonucleoprotein polypeptide A, ELISA Kit - MBS9310752 from MyBioSource
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Human SNRPA ELISA Kit - E098292 from Biobool
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