SNRPA

Gene Symbol SNRPA
Entrez Gene 6626
Alt Symbol Mud1, U1-A, U1A
Species Human
Gene Type protein-coding
Description small nuclear ribonucleoprotein polypeptide A
Other Description U1 small nuclear RNP-specific A|U1 small nuclear ribonucleoprotein A|U1 snRNP A|U1 snRNP-specific protein A
Swissprots P09012
Accessions AAA61245 EAW56995 EAW56996 P09012 AK293140 BAG56688 AK313182 BAG35999 BC000405 AAH00405 BC008290 AAH08290 BQ002918 CN286572 X06347 CAA29653 NM_004596 NP_004587
Function Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs. {ECO:0000269|PubMed:9848648}.
Subcellular Location Nucleus.
Top Pathways Spliceosome

SNRPA (B-12) - sc-376027 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SNRPA (B-12): sc-376027. Western blot analysis of SNRPA expression in non-transfected: sc-117752 (A) and mouse SNRPA transfected: sc-127563 (B) 293T whole cell lysates and HeLa nuclear extract (C).

SNRPA (P-14) - sc-160024 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SNRPA (P-14): sc-160024. Western blot analysis of SNRPA expression in HeLa (A), Jurkat (B), NIH/3T3 (C) and CCRF-CEM (D) nuclear extracts and rat embryo (E) and mouse embryo (F) tissue extracts.

SNRPA (BJ-7) - sc-101149 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
SNRPA (BJ-7): sc-101149. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human heart tissue showing nuclear localization.

Anti-U1A antibody - ab55751 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
U1A antibody (ab55751) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human heart tissue.

Anti-U1A antibody - ab155054 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-U1A antibody (ab155054) at 1/1000 dilutionLane 1 : A549 whole cell lysateLane 2 : HeLa whole cell lysateLane 3 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-U1A antibody - ab167613 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-U1A antibody (ab167613) at 1 µg/ml + Human liver tissue lysate at 50 µg

Anti-U1A antibody [3F9-1F7] - ab115527 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3F9-1F7
ab115527 at 5ug/ml staining U1A in Formalin-fixed, Paraffin-embedded Human small intestine (submucosal plexus) tissue Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-U1A antibody [EPR10632] - ab166890 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10632
All lanes : Anti-U1A antibody [EPR10632] (ab166890) at 1/10000 dilutionLane 1 : HeLa cell lysateLane 2 : Jurkat cell lysateLane 3 : SH SY5Y cell lysateLane 4 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-SNRPA / U1A Antibody (Biotin) - LS-C183329 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SNRPA / U1A Antibody (FITC) - LS-C183330 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SNRPA / U1A Antibody (HRP) - LS-C183331 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SNRPA / U1A Antibody - LS-C190036 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SNRPA / U1A Antibody (clone 3F9-1F7) IHC-plus™ - LS-B4419 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3F9-1F7
Anti-SNRPA antibody IHC of human small intestine, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4419 concentration 5 ug/ml.

Anti-SNRPA / U1A Antibody (aa83-111, AP) - LS-C269824 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRPA / U1A Antibody - LS-C211014 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of U1 small nuclear ribonucleoprotein A polyclonal Antibody at 2 ug/ml + EC109 whole cell lysate at 20 ug. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 31 kDa. Observed band size: 31 kDa Additional bands at: 52 kDa. We are unsure as to the identity of this extra band.

Anti-SNRPA / U1A Antibody (N-Terminus) - LS-C116909 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SNRPA antibody LS-C116909 Western blot of HeLa lysate.

Anti-SNRPA / U1A Antibody (HRP) - LS-C211015 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of U1 small nuclear ribonucleoprotein A polyclonal Antibody at 2 ug/ml + EC109 whole cell lysate at 20 ug. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 31 kDa. Observed band size: 31 kDa Additional bands at: 52 kDa. We are unsure as to the identity of this extra band.

Anti-SNRPA / U1A Antibody (FITC) - LS-C211016 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of U1 small nuclear ribonucleoprotein A polyclonal Antibody at 2 ug/ml + EC109 whole cell lysate at 20 ug. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 31 kDa. Observed band size: 31 kDa Additional bands at: 52 kDa. We are unsure as to the identity of this extra band.

Anti-SNRPA / U1A Antibody (aa83-111, PE) - LS-C269827 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRPA / U1A Antibody (aa83-111, APC) - LS-C269826 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRPA / U1A Antibody (Biotin) - LS-C211017 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of U1 small nuclear ribonucleoprotein A polyclonal Antibody at 2 ug/ml + EC109 whole cell lysate at 20 ug. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 31 kDa. Observed band size: 31 kDa Additional bands at: 52 kDa. We are unsure as to the identity of this extra band.

Anti-SNRPA / U1A Antibody (aa82-111) - LS-C325239 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRPA / U1A Antibody (aa1-283, Azide-free) - LS-C328702 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-SNRPA / U1A Antibody (aa83-111) - LS-C161351 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SNRPA Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-SNRPA / U1A Antibody - LS-C334695 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using SNRPA antibody.
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