SNRPA

Gene Symbol SNRPA
Entrez Gene 6626
Alt Symbol Mud1, U1-A, U1A
Species Human
Gene Type protein-coding
Description small nuclear ribonucleoprotein polypeptide A
Other Description U1 small nuclear RNP-specific A|U1 small nuclear ribonucleoprotein A|U1 snRNP A|U1 snRNP-specific protein A
Swissprots P09012
Accessions AAA61245 EAW56995 EAW56996 P09012 AK293140 BAG56688 AK313182 BAG35999 BC000405 AAH00405 BC008290 AAH08290 BQ002918 CN286572 X06347 CAA29653 NM_004596 NP_004587
Function Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs. {ECO:0000269|PubMed:9848648}.
Subcellular Location Nucleus.
Top Pathways Spliceosome

SNRPA - MBS1274049 from MyBioSource

Species Human
Accession BC000405

human SNRPA ORF clone - CDCH084036 from Creative Biomart

Species Human
Accession NM_004596

human SNRPA ORF clone - CDCH084037 from Creative Biomart

Species Human
Accession NM_004596

Human SNRPA ORF Clone(NM_004596.4) - CDCL176531 from Creative Biomart

Species Human
Accession NM_004596.4

Human SNRPA ORF Clone (BC000405) - CDCS411870 from Creative biogene

Species Human
Accession P09012
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