SNRPA

Gene Symbol	SNRPA
Entrez Gene	6626
Alt Symbol	Mud1, U1-A, U1A
Species	Human
Gene Type	protein-coding
Description	small nuclear ribonucleoprotein polypeptide A
Other Description	U1 small nuclear RNP-specific A|U1 small nuclear ribonucleoprotein A|U1 snRNP A|U1 snRNP-specific protein A
Swissprots	P09012
Accessions	AAA61245 EAW56995 EAW56996 P09012 AK293140 BAG56688 AK313182 BAG35999 BC000405 AAH00405 BC008290 AAH08290 BQ002918 CN286572 X06347 CAA29653 NM_004596 NP_004587
Function	Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs. {ECO:0000269|PubMed:9848648}.
Subcellular Location	Nucleus.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SNRPA CRISPR/Cas9 KO Plasmid (h) - sc-404128 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SNRPA HDR Plasmid (h) - sc-404128-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SNRPA Double Nickase Plasmid (h) - sc-404128-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SNRPA Double Nickase Plasmid (h2) - sc-404128-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SNRPA CRISPR Activation Plasmid (h) - sc-404128-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SNRPA CRISPR Activation Plasmid (h2) - sc-404128-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SNRPA Lentiviral Activation Particles (h) - sc-404128-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SNRPA Lentiviral Activation Particles (h2) - sc-404128-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SNRPA siRNA (h) - sc-97298 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SNRPA shRNA Plasmid (h) - sc-97298-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SNRPA shRNA (h) Lentiviral Particles - sc-97298-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

U1A RNAi - H00006626-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU010851 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20265 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20265 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00987 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr00987

SNRPA siRNA (Human) - CRH4509 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SNRPA - MBS8205339 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SNRPA CRISPR/Cas9 KO Plasmid (h2) - sc-404128-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SNRPA HDR Plasmid (h2) - sc-404128-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human SNRPA (NM_004596.4) - SHH414304 from Creative biogene Category siRNA Species Reactivities Human

Human SNRPA siRNA - orb265011 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SNRPA shRNA Plasmid (Human) - CHH4509 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

SNRPA miRNA 3'UTR clone - MiUTR3H-02108 from Creative biogene Species Reactivities Human

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