DRAXIN

Gene Symbol DRAXIN
Entrez Gene 374946
Alt Symbol AGPA3119, C1orf187, UNQ3119, neucrin
Species Human
Gene Type protein-coding
Description dorsal inhibitory axon guidance protein
Other Description dorsal repulsive axon guidance protein|draxin|neural tissue-specific cysteine-rich protein
Swissprots B6EV15 Q6UWK8 Q5SNX0 Q8NBI3
Accessions EAW71700 EAW71701 Q8NBI3 AB301919 BAG80561 AK075558 BAC11697 AK092318 BAG52531 AK311439 AY358750 AAQ89110 BC021286 BC111064 AAI11065 BM928129 XM_011541405 XP_011539707 XM_011541406 XP_011539708 NM_198545 NP_940947
Function Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta- catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. {ECO:0000255|HAMAP- Rule:MF_03060}.
Subcellular Location Secreted {ECO:0000305}.

Anti-C1orf187 antibody - ab117452 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of C1orf187 in mouse brain tissue with ab117452 at 20 ug/mL.

Anti-C1orf187 / DRAXIN Antibody (aa26-343) - LS-C128678 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-C1orf187 / DRAXIN Antibody (aa26-349) - LS-C128679 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-C1orf187 / DRAXIN Antibody (C-Terminus) IHC-plus™ - LS-B9573 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-C1orf187 / DRAXIN antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9573 concentration 5 ug/ml.

Anti-C1orf187 / DRAXIN Antibody (aa227-276) - LS-C170775 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Draxin/C1orf187 Antibody - AF6148 from Novus Biologicals

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of SH‑SY5Y human neuroblastoma cell line. PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human Draxin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6148) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Draxin at approximately 58 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Draxin/C1orf187 Antibody - NBP1-83505 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: C1orf187 Antibody [NBP1-83505] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Draxin/C1orf187 Antibody - NBP1-46424 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Draxin/C1orf187 Antibody - NBP2-41135 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Draxin/C1orf187 Antibody [NBP2-41135] - Western blot analysis of Neucrin in rat cerebellum tissue lysate with Neucrin antibody at 1 ug/mL.

C1orf187 Polyclonal Antibody - bs-9220R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1orf187 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15047R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1orf187 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15047R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1orf187 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15047R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1orf187 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15047R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1orf187 Polyclonal Antibody, Cy5 Conjugated - bs-15047R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1orf187 Polyclonal Antibody, Cy5.5 Conjugated - bs-15047R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1orf187 Polyclonal Antibody, Cy7 Conjugated - bs-15047R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1orf187 Polyclonal Antibody, Biotin Conjugated - bs-15047R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C1orf187 Polyclonal Antibody, HRP Conjugated - bs-15047R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DRAXIN antibody produced in rabbit - HPA014302 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-C1orf187: <B>Cat. No. HPA014302</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human stomach shows strong nuclear positivity in glandular cells.

DRAXIN Antibody - C-terminal region (ARP69725_P050) - ARP69725_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Draxin antibody - GTX47894 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

Draxin antibody - GTX47893 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

Mouse/Rat Draxin Antibody - AF6149 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Detection of Rat Draxin by Western Blot. Western blot shows lysates of rat embryonic hippocampal glial cells. PVDF Membrane was probed with 1 µg/mL of Mouse/Rat Draxin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6149) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016 ). A specific band was detected for Draxin at approximately 58 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8 .

Mouse/Rat Draxin Affinity Purified Polyclonal Ab, Sheep IgG - AF6149-SP from R&D Systems

Host Sheep
Clonality Polyclonal
Detection of Rat Draxin by Western Blot. Western blot shows lysates of rat embryonic hippocampal glial cells. PVDF Membrane was probed with 1 µg/mL of Mouse/Rat Draxin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6149) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Draxin at approximately 58 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.
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