MCTS1

Gene Symbol MCTS1
Entrez Gene 28985
Alt Symbol MCT-1, MCT1
Species Human
Gene Type protein-coding
Description malignant T cell amplified sequence 1
Other Description malignant T-cell-amplified sequence 1|multiple copies T-cell malignancies
Swissprots Q502X6 B4DGY2 Q9ULC4
Accessions EAX11874 EAX11875 Q9ULC4 AA375691 AB034206 BAA86055 AF456465 AAM50513 AK096956 AK294834 BAG57943 AK311993 BAG34931 AW957695 AY364258 AAQ76817 BC001013 AAH01013 BC095461 AAH95461 BM671542 BP226595 HQ448721 ADQ33199 XR_938549 NM_001137554 NP_001131026 NM_014060 NP_054779
Function Anti-oncogene that play a role in cell cycle regulation; decreases cell doubling time and anchorage-dependent growth; shortens the duration of G1 transit time and G1/S transition. When constituvely expressed, increases CDK4 and CDK6 kinases activity and CCND1/cyclin D1 protein level, as well as G1 cyclin/CDK complex formation. Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role as translation enhancer; recruits the density-regulated protein/DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile; up- regulates protein levels of BCL2L2, TFDP1, MRE11A, CCND1 and E2F1, while mRNA levels remains constant. Hyperactivates DNA damage signaling pathway; increased gamma-irradiation-induced phosph
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11709712, ECO:0000269|PubMed:16982740}. Note=Nuclear relocalization after DNA damage.
Tissue Specificity Ubiquitous. Over-expressed in T-cell lymphoid cell lines and in non-Hodgkin lymphoma cell lines as well as in a subset of primary large B-cell lymphomas. {ECO:0000269|PubMed:9766643}.

MCTS1 (E-14) - sc-168563 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MCTS1 (K-12) - sc-101865 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-Malignant T cell amplified sequence 1 antibody - ab102678 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Malignant T cell amplified sequence 1 antibody (ab102678) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

Anti-Malignant T cell amplified sequence 1 antibody [2F9] - ab117968 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F9
All lanes : Anti-Malignant T cell amplified sequence 1 antibody [2F9] (ab117968) at 1/2000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY controlLane 2 : HEK293T cells transfected with pCMV6-ENTRY Malignant T cell amplified sequence 1 cDNALysates/proteins at 5 µg per lane.

Anti-Malignant T cell amplified sequence 1 antibody - N-terminal - ab135593 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Malignant T cell amplified sequence 1 antibody - N-terminal (ab135593) at 1/50 dilution + Mouse bladder tissue lysate at 35 µg

Anti-MCTS1 Antibody (aa3-14) IHC-plus™ - LS-B1726 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MCT1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1726 concentration 20 ug/ml.

Anti-MCTS1 Antibody (clone 2G2) - LS-C172675 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2G2
IHC of paraffin-embedded Human tonsil using anti-MCTS1 mouse monoclonal antibody.

Anti-MCTS1 Antibody (clone 5B5) - LS-C172727 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5B5
IHC of paraffin-embedded Human tonsil using anti-MCTS1 mouse monoclonal antibody.

Anti-MCTS1 Antibody (aa1-181, clone 2F9) - LS-C340589 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F9
IHC of paraffin-embedded Human tonsil using anti-MCTS1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-MCTS1 Antibody (aa3-14) - LS-C25637 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-MCTS1 Antibody (aa3-14) - LS-C53378 from LifeSpan Bioscience

Prices $445.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-MCTS1 Antibody (aa3-14) - LS-C83548 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MCTS1 Antibody - LS-C2815 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MCTS1 Antibody (aa1-30) - LS-C98395 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of MCT-1 antibody in mouse bladder tissue lysates (35 ug/lane). MCTS1 (arrow) was detected using the purified antibody.

Anti-MCTS1 Antibody (N-Terminus) - LS-C110563 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MCTS1 / MCT1 antibody LS-C110563 Western blot of COLO205 cell lysate.

Anti-MCTS1 Antibody (aa6-20) - LS-C186543 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
MCTS1 antibody (0.3 ug/ml) staining of MOLT4 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

MCTS1 Antibody (2F9) - NBP2-03626 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F9

MCTS1 Antibody - NB500-128 from Novus Biologicals

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MCT1 Antibody [NB500-128] - WB detection of MCT1 in lysate of transfected HEK 293T cells using NB500-128 antibody at a dilution of 1:500.

MCTS1 Antibody - NBP1-58236 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MCTS1 Antibody [NBP1-58236] - COLO205 cells lysate, concentration 0.2-1 ug/ml.

MCTS1 Antibody - NBP2-17242 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MCTS1 Antibody [NBP2-17242] - Non-transfected (-) and transfected (+) MDA-MB-231 whole cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with MCTS1 antibody [N1C3] diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

MCTS1 Antibody (1G1-2A2) - H00028985-M01A from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 1G1-2A2

Anti-MCTS1 antibody produced in rabbit - SAB2701331 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MCTS1: <B>Cat. No. SAB2701331</B>: Western Blot analysis of MCTS1 in extracts from <B>Lanes</B><BR/>A. Jurkat using <B>Cat. No. SAB2701331</B> at a 1:1000 dilution.

Anti-MCTS1, (N-terminal) antibody produced in rabbit - SAB2103663 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MCTS1, antibody produced in rabbit: <B>Cat. No. SAB2103663</B>: Immunoblotting analysis of MCTS1 in COLO205 cell lysate with MCTS1 anitbody at 1 μg/mL.

Anti-MCTS1 antibody produced in rabbit - HPA001045 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MCTS1: <B>Cat. No. HPA001045</B>: Immunohistochemical staining of Human lateral ventricle shows distinct positivity in parts of the neuropil.

Monoclonal Anti-MCTS1 antibody produced in mouse - SAB1401656 from Sigma-Aldrich

Prices $347.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 1G1-2A2
<B>Immunoblotting</B><BR/>Monoclonal Anti-MCTS1, antibody produced in mouse, clone 1G1-2A2, ascites fluid: <B>Cat. No. SAB1401656</B>: Antibody concentration: 1.0 μg/mL. Specific band of ~46.02 kDa using immunogen protein lysate.
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