FRZB

Gene Symbol	FRZB
Entrez Gene	2487
Alt Symbol	FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, OS1, SFRP3, SRFP3, hFIZ
Species	Human
Gene Type	protein-coding
Description	frizzled-related protein
Other Description	frezzled|frizzled homolog-related|frizzled-related protein 1|sFRP-3|secreted frizzled-related protein 3
Swissprots	Q92765 O00181 Q99686
Accessions	AAX93117 AAY24241 ADL14515 EAX10958 Q92765 AK130009 AK312741 BAG35611 AU117730 BC027855 AAH27855 BE549700 BF058813 BT019883 AAV38686 DQ890944 ABM81870 DQ894106 ABM85032 U24163 AAC50736 U68057 AAC51217 U91903 AAB51298 NM_001463 NP_001454
Function	Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Expressed primarily in the cartilaginous cores of the long bone during embryonic and fetal development and in the appendicular skeleton (6-13 weeks). At 13 weeks of gestation, transcripts were present in early chondroblasts of the tarsal bones of the foot, the carpal bones of the hands and the epiphysis of long bones. Highly expressed in placenta and heart, followed by brain, skeletal muscle, kidney and pancreas. Weakly expressed in lung and liver.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FRP-3 (B-5) - sc-514350 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

FRP-3 (K-17) - sc-31570 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

FRP-3 (H-170) - sc-13941 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

FRP-3 (C-20) - sc-7427 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

FRP-3 (L-16) - sc-31572 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-FRZB antibody - ab108169 from Abcam Prices $370.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FRZB antibody - ab55026 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-SFRP-3 / FRZB Antibody (aa216-265) IHC-plus™ - LS-B6898 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SFRP-3 / FRZB Antibody - LS-C10134 from LifeSpan Bioscience Prices $605.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-SFRP-3 / FRZB Antibody - LS-C10135 from LifeSpan Bioscience Prices $295.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-SFRP-3 / FRZB Antibody (Biotin) - LS-C10136 from LifeSpan Bioscience Prices $650.00 Sizes 50 µg Host Goat Clonality Polyclonal

Anti-SFRP-3 / FRZB Antibody (Biotin) - LS-C10138 from LifeSpan Bioscience Prices $650.00 Sizes 50 µg Host Goat Clonality Polyclonal

Anti-SFRP-3 / FRZB Antibody - LS-C10137 from LifeSpan Bioscience Prices $605.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-SFRP-3 / FRZB Antibody (aa1-222) - LS-C311797 from LifeSpan Bioscience Prices $250.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SFRP-3 / FRZB Antibody (aa102-190, Azide-free) - LS-C330652 from LifeSpan Bioscience Host Mouse Clonality Monoclonal

Anti-SFRP-3 / FRZB Antibody - LS-C332856 from LifeSpan Bioscience Prices $305.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SFRP-3 / FRZB Antibody - LS-C334816 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SFRP-3 / FRZB Antibody (aa59-108) - LS-C135316 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SFRP-3 / FRZB Antibody (clone 4F7) - LS-C197246 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 4F7

sFRP-3/FRZB Antibody - NBP1-79552 from Novus Biologicals Prices $139.00, $369.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

sFRP-3/FRZB Antibody - AF192 from Novus Biologicals Prices $99.00, $359.00 Sizes 25 µg, 100 µg Host Goat Clonality Polyclonal

sFRP-3/FRZB Antibody (133912) - MAB192-050 from Novus Biologicals Host Mouse Clonality Monoclonal Clone 133912

sFRP-3/FRZB Antibody - NBP1-79551 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

sFRP-3/FRZB Antibody - H00002487-D01P from Novus Biologicals Prices $399.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

sFRP-3/FRZB Antibody (1H8) - H00002487-M05 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1H8

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