HMGCLL1

Gene Symbol HMGCLL1
Entrez Gene 54511
Alt Symbol bA418P12.1, er-cHL
Species Human
Gene Type protein-coding
Description 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
Other Description 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic|3-hydroxymethyl-3-methylglutaryl-CoA lyase-like protein 1|3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1|endoplasmic reticulum 3-hydroxymethyl-3-methylglutaryl-CoA lyase|probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2
Swissprots B3KNV0 F8W793 B7Z1S7 B1AQ42 Q8TB92 Q6ZSA9
Accessions EAX04442 EAX04443 EAX04444 EAX04445 Q8TB92 AF131827 AAD20054 AK055075 BAG51462 AK127587 BAC87045 AK293856 BAH11613 AK294210 BAH11698 AK297191 BAH12520 AL137605 CAB70838 BC024194 AAH24194 DA508472 DB179645 HQ447228 ADQ31715 XM_011514700 XP_011513002 XM_011514701 XP_011513003 NM_001042406 NP_001035865 NM_001287741 NP_001274670 NM_001287746 NP_001274675 NM_001287753 NP_001274682 NM_019036 NP_061909 NR_109867 NR_109869
Function Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy- 3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues. {ECO:0000269|PubMed:22847177, ECO:0000269|PubMed:22865860}.
Subcellular Location Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein.
Top Pathways Peroxisome, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism

HMGCLL1 (L-12) - sc-136707 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
HMGCLL1 (L-12): sc-136707. Western blot analysis of HMGCLL1 expression in mouse thyroid (A) and mouse brain (B) tissue extracts.

HMGCLL1 (E-13) - sc-136706 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-HMGCLL1 antibody - ab94787 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HMGCLL1 antibody (ab94787) at 1 µg/ml + OVCAR-3 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilutionObserved band size : 36 kDa (why is the actual band size different from the predicted?)

Anti-HMGCLL1 antibody - ab101576 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-HMGCLL1 antibody (ab101576) at 1/500 dilution + Human fetal liver lysate

Anti-HMGCLL1 Antibody (N-Terminus) - LS-C111871 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HMGCLL1 antibody LS-C111871 Western blot of OVCAR-3 cell lysate.

HMGCLL1 Antibody - NBP1-88768 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HMGCLL1 Antibody [NBP1-88768] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)<br/>Lane 5: Human liver tissue

HMGCLL1 Antibody - NBP1-56833 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HMGCLL1, (N-terminal) antibody produced in rabbit - SAB2104380 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HMGCLL1, antibody produced in rabbit: <B>Cat. No. SAB2104380</B>: Immunoblotting analysis of HMGCLL1 in OVCAR-3 cell lysate with HMGCLL1 anitbody at 1 μg/mL.

Anti-HMGCLL1 antibody produced in rabbit - HPA030223 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HMGCLL1: <B>Cat. No. HPA030223</B>: Immunohistochemical staining of human pancreas shows strong nuclear and cytoplasmic positivity in islet cells.

Anti-HMGCLL1 (167-180) antibody produced in rabbit - SAB1101448 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-HMGCLL1 (167-180) : <B>Cat. No. SAB1101448</B>: Immunofluorescence of HUVEC cells using HMGCLL1 (167-180) , Cat. No. SAB1101448 (red) at a 1:200 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

HMGCLL1 antibody - N-terminal region (ARP56277_P050) - ARP56277_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HMGCLL1 antibody, N-term - GTX45075 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-HMGCLL1 antibody, N-term used in Western blot. GTX45075

HMGCLL1 antibody - 70R-4314 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

HMGCLL1 antibody - orb77703 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin embedded fetal brain staining using HMGCLL1 antibody

HMGCLL1 Antibody - abx038037 from Abbexa

Host Rabbit
Clonality Polyclonal

HMGCLL1 antibody - 17206-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal
SKOV-3 cells were subjected to SDS PAGE followed by western blot with 17206-1-AP (HMGCLL1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours

HMGCLL1 Antibody - E305156 from Enogene

Prices $275.00
Sizes 100ug/200ul

HMGCLL1 Antibody - GWB-MU238D from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

HMGCLL1 Antibody - EPP14003 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal

Anti-HMGCLL1 (aa 113-320) polyclonal antibody - DPABH-01501 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Rabbit anti-Human HMGCLL1 polyclonal antibody - DPABH-19393 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-HMGCLL1 monoclonal antibody - DCABH-200697 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

HMGCLL1, Polyclonal Antibody - MBS2529902 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

HMGCLL1, Polyclonal Antibody - MBS855244 from MyBioSource

Prices $330.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

HMGCLL1 Antibody,HRP conjugated - CSB-PA851531LB01HU from Cusabio

Host Rabbit
Clonality Polyclonal
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