HPGDS

Gene Symbol	HPGDS
Entrez Gene	27306
Alt Symbol	GSTS, GSTS1, GSTS1-1, PGD2, PGDS
Species	Human
Gene Type	protein-coding
Description	hematopoietic prostaglandin D synthase
Other Description	GST class-sigma|glutathione S-transferase sigma|glutathione-dependent PGD synthase|glutathione-dependent PGD synthetase|glutathione-requiring prostaglandin D synthase|hematopoietic prostaglandin D2 synthase|prostaglandin-H2 D-isomerase
Swissprots	O60760 Q6FHT9
Accessions	AAY40905 BAA96854 EAX06052 O60760 AK290075 BAF82764 BC020734 AAH20734 CB988786 CR541662 CAG46463 CR541679 CAG46480 D82073 BAA25545 XM_005262932 XP_005262989 NM_014485 NP_055300
Function	Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. {ECO:0000269|PubMed:10824118, ECO:0000269|PubMed:11672424, ECO:0000269|PubMed:12627223, ECO:0000269|PubMed:15113825, ECO:0000269|PubMed:16547010, ECO:0000269|PubMed:19939518, ECO:0000269|PubMed:9353279, ECO:0000269|PubMed:9425264}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9353279}.
Tissue Specificity	Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver. {ECO:0000269|PubMed:10824118, ECO:0000269|PubMed:11672424, ECO:0000269|PubMed:9353279, ECO:0000269|PubMed:9425264}.
Top Pathways	Arachidonic acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HPGDS ELISA Kit (Competitive EIA) - LS-F11655 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 78.13-5000 pg/ml

Human PGDS ELISA kit - 55R-1995 from Fitzgerald Category ELISA Kit Prices $435.00 Sizes 96 tests

GSTs (Glutathione S-Transferases), Human, ELISA Kit - E-EL-H1332 from ARP American Research Products Category ELISA Kit Prices $617.40 Sizes 96 t

Hematopoietic prostaglandin D synthase, HPGDS, Human, ELISA Kit - E15054h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 0.312-20 ng/mL

Prostaglandin D Synthase, PGDS, Human, ELISA Kit - CSB-E04784h from ARP American Research Products Category ELISA Kit Prices $295.00, $395.00, $396.00, $397.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Prostaglandin D2 Synthase, Hematopoietic (PTGDS), Human, ELISA Kit - SEB640Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 36pg/mL Range 78-5,000pg/mL

Glutathione S-Transferases, GSTs, Rabbit, ELISA Kit - E-EL-RB1357 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Glutathione S-Transferases, GSTs, Chicken, ELISA Kit - E-EL-Ch0651 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Glutathione S-Transferases, GSTs, Porcine, ELISA Kit - E-EL-P1360 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Glutathione S-Transferases, GSTs, Monkey, ELISA Kit - E-EL-MK1113 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human GSTs (Glutathione S-Transferases) ELISA Kit - E-EL-H1332 from Elabscience Category ELISA Kit Range ~0

GSTs, ELISA Kit - MBS2509936 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

PGDS, ELISA Kit - MBS2515237 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/mL Range 78.125-5000pg/mL

PGDS, ELISA Kit - MBS2508108 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 2.344pg/mL Range 3.906-250pg/mL

PGDS, ELISA Kit - MBS2503096 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/mL Range 78.125-5000pg/mL

PGDS, ELISA Kit - MBS2514363 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.875pg/mL Range 3.125-200pg/mL

PGDS, ELISA Kit - MBS2512115 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/mL Range 78.125--5000pg/mL

Prostaglandin D Synthase, ELISA Kit - MBS040194 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D Synthase, ELISA Kit - MBS028677 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D Synthase, ELISA Kit - MBS006432 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D Synthase, ELISA Kit - MBS074281 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D Synthase, ELISA Kit - MBS740909 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/mL.

Prostaglandin D Synthase, ELISA Kit - MBS096301 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D Synthase, ELISA Kit - MBS046384 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D Synthase, ELISA Kit - MBS088632 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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