HPGDS

Gene Symbol	HPGDS
Entrez Gene	27306
Alt Symbol	GSTS, GSTS1, GSTS1-1, PGD2, PGDS
Species	Human
Gene Type	protein-coding
Description	hematopoietic prostaglandin D synthase
Other Description	GST class-sigma|glutathione S-transferase sigma|glutathione-dependent PGD synthase|glutathione-dependent PGD synthetase|glutathione-requiring prostaglandin D synthase|hematopoietic prostaglandin D2 synthase|prostaglandin-H2 D-isomerase
Swissprots	O60760 Q6FHT9
Accessions	AAY40905 BAA96854 EAX06052 O60760 AK290075 BAF82764 BC020734 AAH20734 CB988786 CR541662 CAG46463 CR541679 CAG46480 D82073 BAA25545 XM_005262932 XP_005262989 NM_014485 NP_055300
Function	Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. {ECO:0000269|PubMed:10824118, ECO:0000269|PubMed:11672424, ECO:0000269|PubMed:12627223, ECO:0000269|PubMed:15113825, ECO:0000269|PubMed:16547010, ECO:0000269|PubMed:19939518, ECO:0000269|PubMed:9353279, ECO:0000269|PubMed:9425264}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9353279}.
Tissue Specificity	Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver. {ECO:0000269|PubMed:10824118, ECO:0000269|PubMed:11672424, ECO:0000269|PubMed:9353279, ECO:0000269|PubMed:9425264}.
Top Pathways	Arachidonic acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-PGDS-cDNA-Clone - DC04969 from Abgent, a WuXi AppTec company Prices $268.65 Sizes 10 µg Species Human Accession BC020734

Human HPGDS cDNA clone(NM_014485.2) - CDFH008750 from Creative Biomart Species Human Accession NM_014485.2

Human HPGDS cDNA clone(NM_014485.2) - CDFH008751 from Creative Biomart Species Human Accession NM_014485.2

Human HPGDS ORF Clone(NM_014485.2) - CDCR297653 from Creative Biomart Species Human Accession NM_014485.2

Human HPGDS ORF Clone(NM_014485.2) - CDCR297654 from Creative Biomart Species Human Accession NM_014485.2

Human HPGDS ORF Clone(NM_014485.2) - CDCR297655 from Creative Biomart Species Human Accession NM_014485.2

Human HPGDS ORF clone(NM_014485.2) - CDCR007163 from Creative Biomart Species Human Accession NM_014485.2

Human HPGDS Gene cDNA clone plasmid - HG15286-G from Sino Biological Species Human

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid, N-His tag - HG15286-NH from Sino Biological Species Human

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15286-ANG from Sino Biological Species Human

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15286-CF from Sino Biological Species Human

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15286-NM from Sino Biological Species Human

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15286-CM from Sino Biological Species Human

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid, C-His tag - HG15286-CH from Sino Biological Species Human

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid, C-HA tag - HG15286-CY from Sino Biological Species Human

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid - HG15286-UT from Sino Biological Species Human

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15286-ACR from Sino Biological Species Human

Human HPGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-OFPSpark tag - HG15286-ANR from Sino Biological Species Human Accession BC020734

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15286-ACG from Sino Biological Species Human

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid, N-HA tag - HG15286-NY from Sino Biological Species Human

Human PGD2 / PGDS Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15286-NF from Sino Biological Species Human

Human HPGDS ORF Clone(NM_014485.2) - CDCR297653 from Creative biogene Species Human

Human HPGDS ORF clone (BC020734) - CDCB157788 from Creative biogene Species Human

Human HPGDS Gene cDNA Clone - orb143610 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human HPGDS cDNA Clone(NM_014485.2) - CDFH008750 from Creative biogene Species Human

Search more