SFRP4

Gene Symbol	SFRP4
Entrez Gene	6424
Alt Symbol	FRP-4, FRPHE, sFRP-4
Species	Human
Gene Type	protein-coding
Description	secreted frizzled-related protein 4
Other Description	frizzled protein, human endometrium|secreted frizzled-related protein 4; secreted frizzled-related protein 4
Swissprots	Q6FHM0 Q6FHJ7 Q1ZYW2 Q6PD64 Q05BG7 Q4G124 O14877 B4DYC1
Accessions	EAL23981 EAW94085 Q6FHJ7 AF026692 AAC04617 AK302357 BAG63683 AK303977 BAG64896 AK313029 BC032828 BC047684 AAH47684 BC058911 AAH58911 BT019679 AAV38485 CR541731 CAG46532 CR541755 CAG46555 DQ420628 ABD83351 NM_003014 NP_003005
Function	Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. {ECO:0000250}.
Subcellular Location	Secreted {ECO:0000269|PubMed:19480240}. Note=Cytoplasmic in ovarian tumor cells.
Tissue Specificity	Expressed in mesenchymal cells. Highly expressed in the stroma of proliferative endometrium. Expressed in cardiomyocytes. Shows moderate to strong expression in ovarian tumors with expression increasing as the tumor stage increases. In ovarian tumors, expression levels are inversely correlated with expression of CTNNB1 (at protein level). {ECO:0000269|PubMed:10728394, ECO:0000269|PubMed:19480240}.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse SFRP4 ELISA Kit (Sandwich ELISA) - LS-F6527 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.063 ng/ml Range 0.156-10 ng/ml

Human SFRP4 ELISA Kit (Sandwich ELISA) - LS-F6799 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 62.5 pg/ml Range 0.156-10 ng/ml

Rat SFRP4 ELISA Kit (Sandwich ELISA) - LS-F8488 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 13.8 pg/ml Range 0.156-10 ng/ml

Human SFRP4 ELISA Kit (Sandwich ELISA) - LS-F12588 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Secreted Frizzled Related Protein 4 (SFRP4), Human, ELISA Kit - SEF878Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 26.6pg/mL Range 62.5-4,000pg/mL

Secreted frizzled-related protein 4 (SFRP4), Human, ELISA Kit - CSB-E13721h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.39 ng/ml Range 1.56 ng/ml-100ng/ml

Secreted frizzled-related protein 4, SFRP4, Human, ELISA Kit - E1650h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Human SFRP4(secreted frizzled-related protein 4) ELISA Kit - E-EL-H5447 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Secreted Frizzled Related Protein 4 (SFRP4), ELISA Kit - MBS9308184 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Secreted Frizzled Related Protein 4 (SFRP4), ELISA Kit - MBS2023759 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.063ng/mL. Range 0.156-10ng/mL

Secreted Frizzled Related Protein 4 (SFRP4), ELISA Kit - MBS2021277 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 13.8pg/mL. Range 31.2-2,000pg/mL. The standard curve concentrations used for the ELISA's were 2,000pg/mL, 1,000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL.

Secreted Frizzled Related Protein 4 (SFRP4), ELISA Kit - MBS9307839 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/ml. Range 3.12 ng/ml - 100 ng/ml.

Secreted Frizzled Related Protein 4 (SFRP4), ELISA Kit - MBS2020567 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 6.1pg/mL. Range 15.63-1000pg/mL

secreted frizzled-related protein 4, ELISA Kit - MBS700680 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.39 ng/ml Range 1.56 ng/ml-100ng/ml

SFRP4, ELISA Kit - MBS2515714 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

ELISA Kit for Secreted Frizzled Related Protein 4 (SFRP4) - SEF878Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 6.1pg/mL. Range 15.63-1000pg/mL The standard curve concentrations used for the ELISA’s were 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.63pg/mL

ELISA Kit for Secreted Frizzled Related Protein 4 (SFRP4) - SEF878Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.063ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Secreted Frizzled Related Protein 4 (SFRP4) - SEF878Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 14.5pg/mL. Range 31.25-2000pg/mL The standard curve concentrations used for the ELISA’s were 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL

Human secreted frizzled-related protein 4(SFRP4) ELISA Kit - CSB-E13721h from Cusabio Category ELISA Kit Sensitivity 0.39ng/ml Range 1.56 ng/ml-100ng/ml

ELISA Kit for Secreted Frizzled Related Protein 4 (SFRP4) - SEF878Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 6.1pg/mL. Range 15.625-1000pg/mL The standard curve concentrations used for the ELISA's were 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.625pg/mL

Mouse SFRP4 ELISA Kit (Custom ELISA) - LS-F18231 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Rat SFRP4 ELISA Kit (Custom ELISA) - LS-F18232 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human SFRP4(secreted frizzled-related protein 4) ELISA Kit - E-EL-H5447 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.1 ng/mL Range 0.16~10 ng/mL

Human SFRP4 ELISA Kit - abx153071 from Abbexa Category ELISA Kit Range 15.63 pg/ml - 1000 pg/ml

Human SFRP4 ELISA Kit (Sandwich ELISA) - LS-F21294 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.094 ng/ml Range 0.156-10 ng/ml

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