GAB2

Gene Symbol	GAB2
Entrez Gene	9846
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	GRB2-associated binding protein 2
Other Description	GRB2-associated-binding protein 2|Grb2-associated binder 2|growth factor receptor bound protein 2-associated protein 2|pp100
Swissprots	O60317 A6NEW9 Q9UQC2 A7MD36 A2RRM2
Accessions	EAW75057 EAW75058 Q9UQC2 AA865573 AB011143 BAA25497 AB018413 BAA76737 AI858080 BC131711 AAI31712 BC152459 AAI52460 BY799914 DA674753 DB636423 XM_006718753 XP_006718816 XM_011545408 XP_011543710 XR_950117 NM_012296 NP_036428 NM_080491 NP_536739
Function	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. {ECO:0000269|PubMed:15750601, ECO:0000269|PubMed:19172738}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19172738}. Cell membrane {ECO:0000269|PubMed:19172738}.
Top Pathways	Fc epsilon RI signaling pathway, Chronic myeloid leukemia, Fc gamma R-mediated phagocytosis, Osteoclast differentiation, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat Phospho-GAB2 (Ser623) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1733 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Mouse/Human/Rat Phospho-GAB2 (Tyr643) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1732 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Mouse/Human/Rat Phospho-GAB2 (Ser159) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1716 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Mouse/Human/Rat GAB2 ELISA Kit (Cell-Based ELISA) - LS-F2005 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

GRB2-associated-binding protein 2 (GAB2), Human, ELISA Kit - CSB-EL009127HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Gab2 Colorimetric Cell-Based ELISA Kit - CB5282 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

GRB2 (Phospho-Ser159) Colorimetric Cell-Based ELISA Kit - CBP1796 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Gab2 (Phospho-Tyr643) Colorimetric Cell-Based ELISA Kit - CBP1821 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Gab2 (Phospho-Ser623) Colorimetric Cell-Based ELISA Kit - CBP1822 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

GRB2-associated binding protein 2, ELISA Kit - MBS941181 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human GAB2 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 25 pg/ml -1600 pg/ml.

Human GRB2-associated-binding protein 2(GAB2) ELISA kit - CSB-EL009127HU from Cusabio Category ELISA Kit Sensitivity 6.25 pg/ml Range 25 pg/ml-1600 pg/ml

Gab2 ELISA Kit - DEIA-XYA708 from Creative Diagnostics Category ELISA Kit

Gab2 (Phospho-Ser623) ELISA Kit - DEIA-XYA709 from Creative Diagnostics Category ELISA Kit

Gab2 (Phospho-Tyr643) ELISA Kit - DEIA-XYA710 from Creative Diagnostics Category ELISA Kit

Human GAB2 ELISA Kit - E017459 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human GAB2 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mea

anti-GAB2 antibody - ARG64254 from Arigo Biolaboratories Category ELISA Kit

GAB2 ELISA Kit (Human) (OKCA01268) - OKCA01268 from Aviva Systems Biology Category ELISA Kit Prices $600.00 Sizes 96 wells Sensitivity 6.25 pg/mL Range 25 - 1,600 pg/mL

Gab2 Colorimetric Cell-Based ELISA Kit - EKA50240 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

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