GAB2

Gene Symbol	GAB2
Entrez Gene	9846
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	GRB2-associated binding protein 2
Other Description	GRB2-associated-binding protein 2|Grb2-associated binder 2|growth factor receptor bound protein 2-associated protein 2|pp100
Swissprots	O60317 A6NEW9 Q9UQC2 A7MD36 A2RRM2
Accessions	EAW75057 EAW75058 Q9UQC2 AA865573 AB011143 BAA25497 AB018413 BAA76737 AI858080 BC131711 AAI31712 BC152459 AAI52460 BY799914 DA674753 DB636423 XM_006718753 XP_006718816 XM_011545408 XP_011543710 XR_950117 NM_012296 NP_036428 NM_080491 NP_536739
Function	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. {ECO:0000269|PubMed:15750601, ECO:0000269|PubMed:19172738}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19172738}. Cell membrane {ECO:0000269|PubMed:19172738}.
Top Pathways	Fc epsilon RI signaling pathway, Chronic myeloid leukemia, Fc gamma R-mediated phagocytosis, Osteoclast differentiation, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GAB2-Over-expression-Lysate - LY12201a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

GAB2 293T Cell Transient Overexpression Lysate(Denatured) - H00009846-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

GAB2 overexpression lysate - LY403310 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

GAB2 overexpression lysate - LY415859 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

GAB2 293 Cell Lysate - 407441 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

GAB2 Overexpression Lysate (Denatured) - H00009846-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

GAB2 Overexpression Lysate (Native) - NBP2-07465 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

GAB2 Over-expression Lysate Product - GWB-48E4F7 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

GAB2 Overexpression Lysate (Native) - NBP2-04413 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

GAB2 Overexpression Lysate (Denatured) - H00009846-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human GAB2 Knockdown Stable Cell Line - CSC-DC006004 from Creative biogene Category Cell Line Species Human

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