GAB2

Gene Symbol	GAB2
Entrez Gene	9846
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	GRB2-associated binding protein 2
Other Description	GRB2-associated-binding protein 2|Grb2-associated binder 2|growth factor receptor bound protein 2-associated protein 2|pp100
Swissprots	O60317 A6NEW9 Q9UQC2 A7MD36 A2RRM2
Accessions	EAW75057 EAW75058 Q9UQC2 AA865573 AB011143 BAA25497 AB018413 BAA76737 AI858080 BC131711 AAI31712 BC152459 AAI52460 BY799914 DA674753 DB636423 XM_006718753 XP_006718816 XM_011545408 XP_011543710 XR_950117 NM_012296 NP_036428 NM_080491 NP_536739
Function	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. {ECO:0000269|PubMed:15750601, ECO:0000269|PubMed:19172738}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19172738}. Cell membrane {ECO:0000269|PubMed:19172738}.
Top Pathways	Fc epsilon RI signaling pathway, Chronic myeloid leukemia, Fc gamma R-mediated phagocytosis, Osteoclast differentiation, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GAB2 Gene cDNA Clone - orb143278 from Biorbyt Prices $366.00 Sizes 10 μg Species Human

Human-GAB2-cDNA-Clone - DC14776 from Abgent, a WuXi AppTec company Prices $912.60 Sizes 10 µg Species Human Accession BC131711

GAB2 - MBS1272378 from MyBioSource Species Human Accession BC131711

Human GAB2 Gene cDNA clone plasmid - HG15924-G from Sino Biological Species Human

Human GAB2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15924-NY from Sino Biological Species Human

Human GAB2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15924-NF from Sino Biological Species Human

Human GAB2 Gene ORF cDNA clone expression plasmid, C-His tag - HG15924-CH from Sino Biological Species Human

Human GAB2 Gene ORF cDNA clone expression plasmid, N-His tag - HG15924-NH from Sino Biological Species Human

Human GAB2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15924-CF from Sino Biological Species Human

Human GAB2 Gene ORF cDNA clone expression plasmid - HG15924-UT from Sino Biological Species Human

Human GAB2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15924-CM from Sino Biological Species Human

Human GAB2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15924-NM from Sino Biological Species Human

Human GAB2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15924-CY from Sino Biological Species Human

Human GAB2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15924-ACR from Sino Biological Species Human

Human GAB2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15924-ACG from Sino Biological Species Human

Mouse GAB2 ORF clone (NM_012296.3) - CDCL110113 from Creative biogene Species Human

Human GAB2 ORF Clone (BC131711) - CDCS413280 from Creative biogene Species Human Accession Q9UQC2

Human GAB2 ORF clone (BC131711) - CDCB157655 from Creative biogene Species Human

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