GAB2

Gene Symbol	GAB2
Entrez Gene	9846
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	GRB2-associated binding protein 2
Other Description	GRB2-associated-binding protein 2|Grb2-associated binder 2|growth factor receptor bound protein 2-associated protein 2|pp100
Swissprots	O60317 A6NEW9 Q9UQC2 A7MD36 A2RRM2
Accessions	EAW75057 EAW75058 Q9UQC2 AA865573 AB011143 BAA25497 AB018413 BAA76737 AI858080 BC131711 AAI31712 BC152459 AAI52460 BY799914 DA674753 DB636423 XM_006718753 XP_006718816 XM_011545408 XP_011543710 XR_950117 NM_012296 NP_036428 NM_080491 NP_536739
Function	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. {ECO:0000269|PubMed:15750601, ECO:0000269|PubMed:19172738}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19172738}. Cell membrane {ECO:0000269|PubMed:19172738}.
Top Pathways	Fc epsilon RI signaling pathway, Chronic myeloid leukemia, Fc gamma R-mediated phagocytosis, Osteoclast differentiation, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GAB2 peptide - ab133951 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

GAB2 peptide - ab133952 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human GAB2 full length protein - ab160681 from Abcam Category Protein Source Wheat germ Species Human

GAB2 Antibody Blocking Peptide - LS-E26326 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GAB2 Protein - H00009846-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

GAB2 blocking peptide - GTX89031-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

GAB2 Blocking Peptide - abx063622 from Abbexa Category Peptide Species Human

GAB2 Peptide - AC21-1161-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

GAB2 - H00009846-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

GAB2 Peptide - 45-645P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

GAB2 fusion protein - ag18192 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant GRB2 Associated Binding Protein 2 (GAB2) - RPL533Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

GAB2 Blocking Peptide - CBP2428 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

Gab 2 (L617) Peptide - BS9120P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Gab 2 (R270) Peptide - BS9263P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human GRB2-associated-binding protein 2(GAB2) - CSB-YP892175HU CSB-EP892175HU CSB-BP892175HU CSB-MP892175HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GAB2, Peptide - MBS425540 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog

GAB2 Recombinant Protein Antigen - NBP1-81500PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GAB2-Antibody-N-term-Blocking-Peptide - BP6908a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GAB2 Peptide, Human - M34GP06004H from Creative Peptides Category Peptide Source Synthetic. Species Human

GRB2 Associated Binding Protein 2, Recombinant Protein - MBS2029723 from MyBioSource Category Protein Prices $195.00, $425.00, $660.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

GRB2-associated-binding protein 2 (GAB2), Recombinant Protein - MBS1400881 from MyBioSource Category Protein Prices $1,480.00, $1,480.00, $1,710.00, $1,710.00, $2,520.00, $2,520.00, $2,965.00, $2,965.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

GAB2 peptide - orb218291 from Biorbyt Category Peptide Species Human

GAB2 Immunizing peptide - orb50275 from Biorbyt Category Peptide

Recombinant Human GAB2 Protein, GST-tagged - GAB2-4620H from Creative Biomart Category Protein Source Wheat Germ Species Human

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