KLHL25

Gene Symbol KLHL25
Entrez Gene 64410
Alt Symbol ENC-2, ENC2
Species Human
Gene Type protein-coding
Description kelch-like family member 25
Other Description BTB/POZ KELCH domain protein|ectoderm-neural cortex protein 2|ectodermal-neural cortex 2|kelch-like 25|kelch-like protein 25
Swissprots B3KRT7 B2RDH2 Q9H0H3
Accessions EAX01979 Q9H0H3 AK022649 BAB14155 AK056663 BAG51779 AK092231 BAG52499 AK126962 AK315541 BAG37919 AL109693 AL136796 CAB66730 AM393017 CAL37895 AM393776 CAL38651 AY764034 AAV51405 BC028100 AAH28100 DA337553 DB063745 EU446519 ABZ92048 NM_022480 NP_071925
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E. {ECO:0000269|PubMed:22578813}.

KLHL25 (A-12) - sc-131967 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KLHL25 (A-12): sc-131967. Western blot analysis of KLHL25 expression in HeLa (A) and Hep G2 (B) whole cell lysates.

KLHL25 (H-47) - sc-292742 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

KLHL25 (N-13) - sc-131969 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KLHL25 (N-13): sc-131969. Western blot analysis of KLHL25 expression in 293T whole cell lysate.

KLHL25 (E-14) - sc-131968 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KLHL25 (E-14): sc-131968. Western blot analysis of KLHL25 expression in 293 (A) and HeLa (B) whole cell lysates.

KLHL25 (K-20) - sc-100774 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
KLHL25 (K-20): sc-100774. Western blot analysis of KLHL25 expression in non-transfected 293T: sc-117752 (A), human KLHL25 transfected 293T: sc-114802 (B) and Jurkat (C) whole cell lysates.

Anti-KLHL25 antibody - ab106689 from Abcam

Prices $370.00
Sizes 100 µg
Host Chicken
Clonality Polyclonal
Immunofluorescence of KLHL25 in Jurkat cells with ab106689 at 20 ug/mL.

Anti-KLHL25 antibody - ab113888 from Abcam

Prices $407.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
All lanes : Anti-KLHL25 antibody (ab113888) at 1 µg/mlLane 1 : Jurkat cell lysateLane 2 : Jurkat cell lysate with with blocking peptide

Anti-KLHL25 antibody - ab55953 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KLHL25 antibody (ab55953) at 0.3125 µg/ml + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/ 50,000 - 1/100,000 dilution.

Anti-KLHL25 antibody - ab129610 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-KLHL25 antibody (ab129610) at 1/100 dilution + HepG2 cell line lysate at 35 µgSecondaryHRP anti-Rabbit at 1/10000 dilutiondeveloped using the ECL technique

Anti-KLHL25 antibody - ab56408 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-KLHL25 antibody [1B7] - ab101436 from Abcam

Host Mouse
Clonality Monoclonal
Clone 1B7
Anti-KLHL25 antibody [1B7] (ab101436) + KLHL25-hIgGFc transfected HEK293 cells

Anti-KLHL25 Antibody (Internal) IHC-plus™ - LS-B5090 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Anti-KLHL25 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5090 concentration 5 ug/ml.

Anti-KLHL25 Antibody (aa62-91, APC) - LS-C222999 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLHL25 Antibody (aa62-91, AP) - LS-C223000 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLHL25 Antibody (aa62-91, Biotin) - LS-C223001 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLHL25 Antibody (aa62-91, FITC) - LS-C223002 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLHL25 Antibody (aa62-91, Azide-free, HRP) - LS-C223003 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLHL25 Antibody (aa62-91, PE) - LS-C223004 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLHL25 Antibody (aa68-117) - LS-C30075 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
HepG2 Cell Lysate

Anti-KLHL25 Antibody - LS-C308668 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-KLHL25 Antibody (aa61-91) - LS-C322525 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLHL25 Antibody (aa1-590, Azide-free) - LS-C327708 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-KLHL25 Antibody (aa163-212) - LS-C31795 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
KLHL25 antibody LS-C31795 was used in IHC to stain formalin-fixed, paraffin-embedded human brain.

Anti-KLHL25 Antibody (aa144-193) - LS-C109975 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
KLHL25 antibody LS-C109975 Western blot of Transfected 293T cell lysate.

Anti-KLHL25 Antibody (clone 1B7) - LS-C169216 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B7
Western blot using KLHL25 monoclonal antibody against KLHL25(AA: 2-230)-hIgGFc transfected HEK293 cell.
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