KLHL25

Gene Symbol	KLHL25
Entrez Gene	64410
Alt Symbol	ENC-2, ENC2
Species	Human
Gene Type	protein-coding
Description	kelch-like family member 25
Other Description	BTB/POZ KELCH domain protein|ectoderm-neural cortex protein 2|ectodermal-neural cortex 2|kelch-like 25|kelch-like protein 25
Swissprots	B3KRT7 B2RDH2 Q9H0H3
Accessions	EAX01979 Q9H0H3 AK022649 BAB14155 AK056663 BAG51779 AK092231 BAG52499 AK126962 AK315541 BAG37919 AL109693 AL136796 CAB66730 AM393017 CAL37895 AM393776 CAL38651 AY764034 AAV51405 BC028100 AAH28100 DA337553 DB063745 EU446519 ABZ92048 NM_022480 NP_071925
Function	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E. {ECO:0000269|PubMed:22578813}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KLHL25 full length protein - ab163836 from Abcam Category Protein Source Wheat germ Species Human

KLHL25 Antibody Blocking Peptide - LS-E4175 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLHL25 Antibody Blocking Peptide - LS-E12300 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLHL25 Antibody Blocking Peptide - LS-E30905 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human KLHL25 Protein - H00064410-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

KLHL25 Blocking Peptide - NBP1-77147PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

KLHL25-Antibody-N-term-Blocking-Peptide - BP16430a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Kelch-like protein 25 - H00064410-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Kelch-like protein 25 - H00064410-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Kelch-like protein 25 Control Peptide - AP30315CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ENC-2 Peptide - 5695P from ProSci Category Peptide Species Human

Recombinant Human Ectoderm-neural cortex protein 2(KLHL25) - CSB-YP875641HU CSB-EP875641HU CSB-BP875641HU CSB-MP875641HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

KLHL25 Recombinant Protein Antigen - NBP1-83974PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

KLHL25 Peptide, Human - M34GP08283H from Creative Peptides Category Peptide Source Synthetic. Species Human

Ectoderm-neural cortex protein 2 (KLHL25), Recombinant Protein - MBS1439218 from MyBioSource Category Protein Prices $1,390.00, $1,390.00, $1,610.00, $1,610.00, $2,320.00, $2,320.00, $2,765.00, $2,765.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

KLHL25 fusion protein - Ag25765 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

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