EGF

Gene Symbol EGF
Entrez Gene 1950
Alt Symbol HOMG4, URG
Species Human
Gene Type protein-coding
Description epidermal growth factor
Other Description beta-urogastrone|pro-epidermal growth factor
Swissprots Q52LZ6 P01133 B4DRK7 E9PBF0 E7EVD2
Accessions AAR84237 CCQ43157 EAX06257 P01133 AI628974 AK299306 BAG61319 AK307734 AY548762 AAS83395 BC093731 AAH93731 BC113461 AAI13462 BC143357 CA437074 CU446298 DB227969 DB349864 J02548 AAA72173 JQ346088 AFA26280 X04571 CAA28240 XM_005262796 XP_005262853 XM_005262797 XP_005262854 XM_005262798 XP_005262855 XM_005262800 XP_005262857 XM_005262801 XP_005262858 XM_005262802 XP_005262859 XM_006714124 XP_006714187 XM_011531707 XP_011530009 XM_011531708 XP_011530010 XM_011531709 XP_011530011 XR_427532 XR_938699 NM_001178130 NP_001171601 NM_001178131 NP_001171602 NM_001963 NP_001954
Function EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. {ECO:0000269|PubMed:17671655}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed in kidney, salivary gland, cerebrum and prostate. {ECO:0000269|PubMed:17671655}.
Top Pathways Endocytosis, Rap1 signaling pathway, Hepatitis C, PI3K-Akt signaling pathway, Choline metabolism in cancer

Active EGF full length protein - ab9863 from Abcam

Category Protein
Prices $257.00
Sizes 500 µg
Source E. coli

Active human EGF full length protein - ab9697 from Abcam

Category Protein
Prices $257.00
Sizes 500 µg
Source E. coli
Species Human
Lane 1 : Lane 2 : Lane 3 : Lane 1 : Whole cell lysate of human skin fibroblasts starved overnight in serum-free medium Lane 2 : Whole cell lysate of human skin fibroblasts starved overnight in serum-free medium and then incubated for 30 min with 25 ng/ml active EGF Lane 3 : Whole cell lysate of human skin fibroblasts starved overnight in serum-free medium and then incubated for 30 min with 50 ng/ml active EGF Lysates/proteins at 20 µg per lane. Secondary An HRP-conjugatede Goat anti-rabbit IgG polyclonal at 1/10000 dilution developed using the ECL technique Performed under non-reducing conditions. Observed band size : 42,44 kDa ( why is the actual band size different from the predicted? ) Exposure time : 1 second This image is courtesy of an anonymous Abreview See Abreview

Active human EGF full length protein - ab168895 from Abcam

Category Protein
Prices $410.00
Sizes 1 mg
Source E. coli
Species Human
SDS-PAGE analysis of ab168895 stained overnight with Coomassie Blue.

Active human EGF full length protein - ab179628 from Abcam

Category Protein
Prices $202.00, $387.00
Sizes 500 µg, 1 mg
Source E. coli
Species Human

Active human EGF full length protein - ab91371 from Abcam

Category Protein
Prices $326.00
Sizes 250 µg
Source E. coli
Species Human
SDS-PAGE showing ab91371 at approximately 6.5kDa.

Active human EGF full length protein - ab193874 from Abcam

Category Protein
Prices $155.00
Sizes 10 µg
Source Mammalian
Species Human
The bioactivity of ab193874 was determined by a Balb-3T3 cell proliferation assay.

Active mouse EGF full length protein - ab72994 from Abcam

Category Protein
Prices $257.00, $386.00
Sizes 500 µg, 1 mg
Source E. coli
Species Mouse
ab72994 used in Western Blot. Figure: 1 ug in each lane (-) non-reducing conditions and (+) reducing conditions in a 4-20% Tris-Glycine gel stained with Coomassie Blue. Mouse EGF is predicted to be a homodimer with a MW of 12.4 kDa.

Active mouse EGF full length protein - ab191769 from Abcam

Category Protein
Prices $192.00
Sizes 500 µg
Source E. coli
Species Mouse

Active rat EGF full length protein - ab123750 from Abcam

Category Protein
Prices $210.00
Sizes 20 µg
Source E. coli
Species Rat

Active rat EGF full length protein - ab198562 from Abcam

Category Protein
Prices $300.00, $813.00
Sizes 100 µg, 500 µg
Source E. coli
Species Rat

Active rat EGF full length protein - ab191776 from Abcam

Category Protein
Prices $192.00
Sizes 100 µg
Source E. coli
Species Rat

Human EGF full length protein - ab55483 from Abcam

Category Protein
Source Pichia pastoris
Species Human
All lanes : Anti-EGF antibody ( ab9695 ) at 0.2 µg/ml Lane 1 : Human EGF full length protein (ab55483) at 0.1 µg Lane 2 : Human EGF full length protein (ab55483) at 0.01 µg Secondary Goat Anti-Rabbit IgG H&L (HRP) preadsorbed ( ab97080 ) at 1/5000 dilution developed using the ECL technique Performed under reducing conditions. Exposure time : 1 minute

Human EGF full length protein - ab51082 from Abcam

Category Protein
Source E. coli
Species Human
Standard curve for EGF (Analyte: ab51082 ); dilution range 1pg/ml to 1µg/ml using Capture Antibody ab18635 at 5µg and Detector Antibody ab9695 at 0.5µg/ml

Mouse EGF full length protein - ab126695 from Abcam

Category Protein
Source E. coli
Species Mouse
15% SDS-PAGE analysis of 3 µg of ab126695 (EGF protein).

Rat EGF full length protein - ab50240 from Abcam

Category Protein
Source E. coli
Species Rat

EGF Antibody Blocking Peptide - LS-E2015 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

EGF Antibody Blocking Peptide - LS-E6395 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

EGF Antibody Blocking Peptide - LS-E15273 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human EGF Protein - NBP2-34952 from Novus Biologicals

Category Protein
Prices $69.00, $169.00, $199.00
Sizes 100 µg, 500 µg, 1 mg
Source E. coli
Species Human
Functional: Human EGF Protein [NBP2-34952]

EGF Partial Recombinant Protein - H00001950-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human EGF Protein - NBC1-18456 from Novus Biologicals

Category Protein
Prices $269.00
Sizes 100 µg
Source E.coli
Species Human
SDS-Page: EGF Protein [NBC1-18456] - EGF, 6.3kDa (54aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

EGF Recombinant Protein - P3960 from Novus Biologicals

Category Protein
Prices $549.00
Sizes 500 µg
Species Human

EGF Recombinant Protein - P3600 from Novus Biologicals

Category Protein
Prices $449.00
Sizes 100 µg
Species Human

EGF Recombinant Protein - P3451 from Novus Biologicals

Category Protein
Prices $449.00
Sizes 100 µg
Species Human

EGF Recombinant Protein - P4381 from Novus Biologicals

Category Protein
Prices $549.00
Sizes 500 µg
Species Human
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