IL1R2

Gene Symbol IL1R2
Entrez Gene 7850
Alt Symbol CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB
Species Human
Gene Type protein-coding
Description interleukin 1 receptor, type II
Other Description CD121 antigen-like family member B|IL-1 type II receptor|IL-1R-beta|antigen CDw121b|interleukin 1 receptor type II variant 3|interleukin-1 receptor beta|interleukin-1 receptor type 2|interleukin-1 receptor type II|type II interleukin-1 receptor, beta
Swissprots Q9UE68 P27930 D3DVJ5 Q6LCE6
Accessions AAK52072 AAM64221 CAD19056 CAD28169 CAD57172 CAI84626 CAL63915 CBX46851 EAX01800 EAX01801 EAX01802 EAX01803 P27930 AK130412 AK309161 BC012346 BC027733 AAH27733 BC039031 AAH39031 DC380050 FJ200480 ACO54877 HQ448529 ADQ33008 U64094 AAB05878 U74649 AAD00242 X59770 CAA42441 XM_006712734 XP_006712797 XM_006712736 XP_006712799 XM_011511801 XP_011510103 XM_011511802 XP_011510104 XM_011511803 XP_011510105 XM_011511804 XP_011510106 XM_011511805 XP_011510107 XM_011511806 XP_011510108 XM_011511807 XP_011510109 XM_011511808 XP_011510110 XR_923024 NM_001261419 NP_001248348 NM_004633 NP_004624 NR_048564 NM_173343
Function Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. {ECO:0000269|PubMed:10975853, ECO:0000269|PubMed:12530978, ECO:0000269|PubMed:7989776, ECO:0000269|PubMed:9862719}.
Subcellular Location Isoform Short: Secreted {ECO:0000269|PubMed:8702856}.
Top Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway, Amoebiasis, HTLV-I infection

IL-1RII (6G5) - sc-52678 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
IL-1RII (6G5): sc-52678. Western blot analysis of IL-1RII expression in non-transfected: sc-117752 (A) and human IL-1RII transfected: sc-115519 (B) 293T whole cell lysates.

IL-1RII (G-5) - sc-376247 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-1RII (G-5): sc-376247. Western blot analysis of IL-1RII expression in non-transfected: sc-117752 (A) and human IL-1RII transfected: sc-115519 (B) 293T whole cell lysates.

IL-1RII (H-71) - sc-292522 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
IL-1RII (H-71): sc-292522. Western blot analysis of IL-1RII expression in HeLa (A) and Jurkat (B) whole cell lysates.

IL-1RII (P-20) - sc-27854 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-IL1 Receptor II antibody - ab189648 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human small intestine tissue labeling IL1 Receptor II with ab189648 at 10 µg/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-IL1 Receptor II antibody - ab89159 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-IL1 Receptor II antibody (ab89159) at 1 µg/ml + Human kidney cell lysate at 25 µg

Anti-IL1 Receptor II antibody - ab34665 from Abcam

Prices $370.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-IL1 Receptor II antibody - ab97388 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-IL1 Receptor II antibody (ab97388) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-IL1 Receptor II antibody - ab34838 from Abcam

Prices $359.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-IL1 Receptor II antibody - ab106737 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IL1 Receptor II antibody (ab106737) at 1/500 dilutionLane 1 : 293T cell lysateLane 2 : 293A cell lysateLane 3 : Jurkat cell lysateLane 4 : HeLa cell lysateLane 5 : Human fetal kidney lysateLane 6 : Human fetal spleen lysate

Anti-IL1 Receptor II antibody - ab7748 from Abcam

Prices $370.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-IL1 Receptor II antibody - ab103914 from Abcam

Prices $242.00
Sizes 200 µl
Host Goat
Clonality Polyclonal

Anti-IL1 Receptor II antibody [3C6] - ab180375 from Abcam

Prices $357.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3C6
All lanes : Anti-IL1 Receptor II antibody [3C6] (ab180375) at 1/1000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY IL1 Receptor II cDNALysates/proteins at 5 µg per lane.

Anti-IL1 Receptor II antibody [8.5] - ab11868 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 8.5

Anti-CD121b / IL1R2 Antibody (Extracellular Domain) - LS-C24838 from LifeSpan Bioscience

Prices $575.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-CD121b / IL1R2 Antibody - LS-C24844 from LifeSpan Bioscience

Prices $635.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CD121b / IL1R2 Antibody (Extracellular Domain) - LS-C24839 from LifeSpan Bioscience

Prices $620.00
Sizes 1 mg
Host Rabbit
Clonality Polyclonal

Anti-CD121b / IL1R2 Antibody - LS-C24845 from LifeSpan Bioscience

Prices $635.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CD121b / IL1R2 Antibody - LS-C24846 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CD121b / IL1R2 Antibody - LS-C24847 from LifeSpan Bioscience

Prices $560.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CD121b / IL1R2 Antibody (aa217-230) - LS-C113009 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-CD121b / IL1R2 Antibody - LS-C130150 from LifeSpan Bioscience

Prices $590.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CD121b / IL1R2 Antibody (aa14-343, CF) - LS-C130149 from LifeSpan Bioscience

Prices $445.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal

Anti-CD121b / IL1R2 Antibody (clone 8.5) - LS-C130152 from LifeSpan Bioscience

Prices $590.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone 8.5

Anti-CD121b / IL1R2 Antibody (aa14-343, APC) - LS-C130153 from LifeSpan Bioscience

Prices $590.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
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