IL1R2

Gene Symbol	IL1R2
Entrez Gene	7850
Alt Symbol	CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB
Species	Human
Gene Type	protein-coding
Description	interleukin 1 receptor, type II
Other Description	CD121 antigen-like family member B|IL-1 type II receptor|IL-1R-beta|antigen CDw121b|interleukin 1 receptor type II variant 3|interleukin-1 receptor beta|interleukin-1 receptor type 2|interleukin-1 receptor type II|type II interleukin-1 receptor, beta
Swissprots	Q9UE68 P27930 D3DVJ5 Q6LCE6
Accessions	AAK52072 AAM64221 CAD19056 CAD28169 CAD57172 CAI84626 CAL63915 CBX46851 EAX01800 EAX01801 EAX01802 EAX01803 P27930 AK130412 AK309161 BC012346 BC027733 AAH27733 BC039031 AAH39031 DC380050 FJ200480 ACO54877 HQ448529 ADQ33008 U64094 AAB05878 U74649 AAD00242 X59770 CAA42441 XM_006712734 XP_006712797 XM_006712736 XP_006712799 XM_011511801 XP_011510103 XM_011511802 XP_011510104 XM_011511803 XP_011510105 XM_011511804 XP_011510106 XM_011511805 XP_011510107 XM_011511806 XP_011510108 XM_011511807 XP_011510109 XM_011511808 XP_011510110 XR_923024 NM_001261419 NP_001248348 NM_004633 NP_004624 NR_048564 NM_173343
Function	Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. {ECO:0000269|PubMed:10975853, ECO:0000269|PubMed:12530978, ECO:0000269|PubMed:7989776, ECO:0000269|PubMed:9862719}.
Subcellular Location	Isoform Short: Secreted {ECO:0000269|PubMed:8702856}.
Top Pathways	Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway, Amoebiasis, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-IL1R2-cDNA-Clone - DC07236 from Abgent, a WuXi AppTec company Prices $537.30 Sizes 10 µg Species Human Accession BC039031

Mouse IL-1 RII (NP_034685) VersaClone cDNA - RDC1140 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

Human IL-1 RII (NP_004624) VersaClone cDNA - RDC1142 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

IL1R2 - MBS1276084 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC039031

Human IL1R2 cDNA clone(NM_004633.3) - CDFH009166 from Creative Biomart Species Human Accession NM_004633.3

Human IL1R2 ORF Clone(NM_004633.3) - CDCR288507 from Creative Biomart Species Human Accession NM_004633.3

Human IL1R2 ORF Clone(NM_004633.3) - CDCR288508 from Creative Biomart Species Human Accession NM_004633.3

Human IL1R2 ORF Clone(NM_004633.3) - CDCL167105 from Creative Biomart Species Human Accession NM_004633.3

Human IL1R2 ORF clone(NM_004633.3) - CDCL184824 from Creative Biomart Species Human Accession NM_004633.3

Human IL1R2 / CD121b transcript variant 1 Gene cDNA clone plasmid - HG10111-M from Sino Biological Species Human

Human IL-1R2/CD121b transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10111-NH from Sino Biological Species Human

Human IL-1R2/CD121b transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10111-M-F from Sino Biological Species Human

Human IL1R2 / CD121b transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10111-M-N from Sino Biological Species Human Accession NM_004633.3

Human IL-1R2/CD121b transcript variant 1 Gene ORF cDNA clone expression plasmid - HG10111-UT from Sino Biological Species Human

Human IL-1R2/CD121b transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10111-CY from Sino Biological Species Human

Human IL-1R2/CD121b transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10111-CH from Sino Biological Species Human

Human IL-1R2/CD121b transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10111-NF from Sino Biological Species Human

Human IL-1R2/CD121b transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10111-CF from Sino Biological Species Human

Human IL-1R2/CD121b transcript variant 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10111-NY from Sino Biological Species Human

Human IL-1R2/CD121b transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10111-NM from Sino Biological Species Human

Human IL-1R2/CD121b transcript variant 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10111-ACG from Sino Biological Species Human

Human IL-1R2/CD121b transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10111-CM from Sino Biological Species Human

Human IL1R2 ORF clone(NM_004633.3) - CDCL184824 from Creative biogene Species Human

Human IL1R2 ORF Clone (BC039031) - CDCS411887 from Creative biogene Species Human Accession P27930

Human IL1R2 cDNA Clone(NM_004633.3) - CDFH009166 from Creative biogene Species Human

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