MRI1

Gene Symbol MRI1
Entrez Gene 84245
Alt Symbol MRDI, MTNA, Ypr118w
Species Human
Gene Type protein-coding
Description methylthioribose-1-phosphate isomerase 1
Other Description M1Pi|MTR-1-P isomerase|S-methyl-5-thioribose-1-phosphate isomerase 1|mediator of RhoA-dependent invasion|methylthioribose-1-phosphate isomerase|methylthioribose-1-phosphate isomerase homolog|translation initiation factor eIF-2B subunit alpha/beta/delta-like protein
Swissprots Q8NDC9 Q9BV20
Accessions EAW84369 EAW84370 EAW84371 Q9BV20 AF318324 AAL55831 AL834276 CAD38951 AM392616 CAL37494 AM393224 CAL38102 AY358176 AAQ88543 BC001703 AAH01703 BM147362 EU832338 ACE87595 EU832423 ACE86908 HQ448241 ADQ32721 XM_011528355 XP_011526657 XM_011528356 XP_011526658 XM_011528357 XP_011526659 XR_244089 NM_001031727 NP_001026897 NM_032285 NP_115661
Function Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover. {ECO:0000255|HAMAP-Rule:MF_03119, ECO:0000269|PubMed:19620624}.
Subcellular Location Nucleus {ECO:0000255|HAMAP-Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cytoplasm {ECO:0000255|HAMAP- Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cell projection {ECO:0000269|PubMed:19620624}. Note=Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.
Top Pathways Cysteine and methionine metabolism

MRI1 (E-15) - sc-240704 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-EI2BL antibody - ab57912 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-EI2BL antibody [6A10] - ab117969 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6A10
All lanes : Anti-EI2BL antibody [6A10] (ab117969) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY EI2BL cDNALysates/proteins at 5 µg per lane.

Anti-EI2BL antibody [9H7] - ab124044 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9H7
All lanes : Anti-EI2BL antibody [9H7] (ab124044) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY EI2BL cDNALysates/proteins at 5 µg per lane.

Anti-MRI1 Antibody (aa94-143) - LS-C135801 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MRI1 antibody LS-C135801 Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.

Anti-MRI1 Antibody (aa100-149) - LS-C135802 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MRI1 antibody LS-C135802 Western blot of Fetal Liver lysate. Antibody concentration 1 ug/ml.

Anti-MRI1 Antibody - LS-C332624 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using MRI1 antibody.

Anti-MRI1 Antibody (clone 9H7) - LS-C114590 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9H7
IHC of paraffin-embedded Carcinoma of kidney tissue using anti-MRI1 mouse monoclonal antibody. (Dilution 1:50).

Anti-MRI1 Antibody (clone 6G9) - LS-C114536 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6G9
IHC of paraffin-embedded Adenocarcinoma of ovary tissue using anti-MRI1 mouse monoclonal antibody. (Dilution 1:50).

Anti-MRI1 Antibody (clone 2D11-1G4) - LS-C308988 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D11-1G4

Anti-MRI1 Antibody - LS-C311390 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MRI1 Antibody (aa103-152) - LS-C30881 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
MGC3207 antibody LS-C30881 Western blot of NIH/3T3 cell lysate.

Anti-MRI1 Antibody (aa267-316) - LS-C30880 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
MGC3207 antibody LS-C30880 Western blot of NIH/3T3 cell lysate.

EI2BL Antibody (9H7) - NBP1-47857 from Novus Biologicals

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9H7
Western Blot: EI2BL Antibody (9H7) [NBP1-47857] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EI2BL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EI2BL.

EI2BL Antibody (2D11-1G4) - H00084245-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D11-1G4

EI2BL Antibody - H00084245-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: EI2BL Antibody [H00084245-D01P] - Analysis of MGC3207 expression in transfected 293T cell line by MGC3207 polyclonal antibody.Lane 1: MGC3207 transfected lysate(39.10 KDa).Lane 2: Non-transfected lysate.

EI2BL Antibody - H00084245-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: EI2BL Antibody [H00084245-B01] - analysis of MGC3207 expression in transfected 293T cell line by MGC3207 MaxPab polyclonal antibody (B01). Lane 1: MGC3207 transfected lysate (39.10 KDa). Lane 2: Non-transfected lysate.

EI2BL Antibody - H00084245-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: EI2BL Antibody [H00084245-B01P] - Analysis of MGC3207 expression in transfected 293T cell line by MGC3207 polyclonal antibody. Lane 1: MGC3207 transfected lysate(40.59 KDa). Lane 2: Non-transfected lysate.

Anti-MRI1 antibody produced in rabbit - HPA042744 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MRI1: <B>Cat. No. HPA042744</B>: Immunohistochemical staining of human thyroid gland shows moderate cytoplasmic and nuclear positivity in glandular cells.

Anti-MRI1 (296-310) antibody produced in rabbit - SAB1105561 from Sigma-Aldrich

Prices $279.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human MRI1 was separated on SDS-PAGE, blotted with Anti-MRI1 (296-310) (<B>Cat. No. SAB1105561</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000<BR/>2. Antibody dilution 1:1,000 + MRI1 immunizing peptide (human, 296-310)

Anti-MGC3207 antibody produced in mouse - SAB1409887 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MGC3207: <B>Cat. No. SAB1409887</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~40.6 kDa using MGC3207 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-MGC3207 antibody produced in rabbit - SAB2107535 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MGC3207: <B>Cat. No. SAB2107535</B>: Western blot analysis of MGC3207 in Fetal Liver with MGC3207 (methylthioribose-1-phosphate isomerase homolog, S. cerevisiae) antibody, against the N terminal of MGC3207 (50 μg) antibody at 1.0 μg/mL.

Anti-MGC3207 antibody produced in rabbit - SAB1411504 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MGC3207: <B>Cat. No. SAB1411504</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~39.1 kDa using MGC3207 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Monoclonal Anti-MGC3207 antibody produced in mouse - WH0084245M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D11-1G4
<B>Immunoblotting</B><BR/>Monoclonal Anti-MGC3207, <B>Cat. No. WH0084245M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~39.1 kDa using HL-60 lysate.

Anti-MGC3207 antibody produced in rabbit - SAB2107534 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MGC3207: <B>Cat. No. SAB2107534</B>: Western blot analysis of MGC3207 in MCF7 with MGC3207 (methylthioribose-1-phosphate isomerase homolog, S. cerevisiae) antibody, against the N terminal of MGC3207 (50 μg) antibody at 1.0 μg/mL.
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