MRI1

Gene Symbol	MRI1
Entrez Gene	84245
Alt Symbol	MRDI, MTNA, Ypr118w
Species	Human
Gene Type	protein-coding
Description	methylthioribose-1-phosphate isomerase 1
Other Description	M1Pi|MTR-1-P isomerase|S-methyl-5-thioribose-1-phosphate isomerase 1|mediator of RhoA-dependent invasion|methylthioribose-1-phosphate isomerase|methylthioribose-1-phosphate isomerase homolog|translation initiation factor eIF-2B subunit alpha/beta/delta-like protein
Swissprots	Q8NDC9 Q9BV20
Accessions	EAW84369 EAW84370 EAW84371 Q9BV20 AF318324 AAL55831 AL834276 CAD38951 AM392616 CAL37494 AM393224 CAL38102 AY358176 AAQ88543 BC001703 AAH01703 BM147362 EU832338 ACE87595 EU832423 ACE86908 HQ448241 ADQ32721 XM_011528355 XP_011526657 XM_011528356 XP_011526658 XM_011528357 XP_011526659 XR_244089 NM_001031727 NP_001026897 NM_032285 NP_115661
Function	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover. {ECO:0000255|HAMAP-Rule:MF_03119, ECO:0000269|PubMed:19620624}.
Subcellular Location	Nucleus {ECO:0000255|HAMAP-Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cytoplasm {ECO:0000255|HAMAP- Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cell projection {ECO:0000269|PubMed:19620624}. Note=Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.
Top Pathways	Cysteine and methionine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MRI1 Gene cDNA Clone - orb144300 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-MGC3207-cDNA-Clone - DC00787 from Abgent, a WuXi AppTec company Prices $498.15 Sizes 10 µg Species Human Accession BC001703

Human MRI1 cDNA clone(NM_001031727.2) - CDFH011730 from Creative Biomart Species Human Accession NM_001031727.2

Human MRI1 ORF Clone(NM_001031727.2) - CDCR342855 from Creative Biomart Species Human Accession NM_001031727.2

Human MRI1 ORF Clone(NM_001031727.2) - CDCR342856 from Creative Biomart Species Human Accession NM_001031727.2

Human MRI1 ORF Clone(NM_001031727.2) - CDCR342857 from Creative Biomart Species Human Accession NM_001031727.2

Human MRI1 Gene ORF cDNA clone in cloning vector - HG14226-G from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14226-NY from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, C-His tag - HG14226-CH from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14226-ACR from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14226-ANR from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid - HG14226-UT from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14226-CY from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14226-NF from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14226-NM from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14226-CF from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14226-CM from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, N-His tag - HG14226-NH from Sino Biological Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14226-ANG from Sino Biological Species Human

Human MRI1 ORF Clone(NM_001031727.2) - CDCR342855 from Creative biogene Species Human

Human MRI1 ORF clone (NM_032285.2) - CDCL133909 from Creative biogene Species Human

Human MRI1 ORF clone (BC001703) - CDCB159277 from Creative biogene Species Human

Human MRI1 cDNA Clone(NM_001031727.2) - CDFH011730 from Creative biogene Species Human

Human MRI1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14226-ACG from Sino Biological Species Human

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