MRI1

Gene Symbol	MRI1
Entrez Gene	84245
Alt Symbol	MRDI, MTNA, Ypr118w
Species	Human
Gene Type	protein-coding
Description	methylthioribose-1-phosphate isomerase 1
Other Description	M1Pi|MTR-1-P isomerase|S-methyl-5-thioribose-1-phosphate isomerase 1|mediator of RhoA-dependent invasion|methylthioribose-1-phosphate isomerase|methylthioribose-1-phosphate isomerase homolog|translation initiation factor eIF-2B subunit alpha/beta/delta-like protein
Swissprots	Q8NDC9 Q9BV20
Accessions	EAW84369 EAW84370 EAW84371 Q9BV20 AF318324 AAL55831 AL834276 CAD38951 AM392616 CAL37494 AM393224 CAL38102 AY358176 AAQ88543 BC001703 AAH01703 BM147362 EU832338 ACE87595 EU832423 ACE86908 HQ448241 ADQ32721 XM_011528355 XP_011526657 XM_011528356 XP_011526658 XM_011528357 XP_011526659 XR_244089 NM_001031727 NP_001026897 NM_032285 NP_115661
Function	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover. {ECO:0000255|HAMAP-Rule:MF_03119, ECO:0000269|PubMed:19620624}.
Subcellular Location	Nucleus {ECO:0000255|HAMAP-Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cytoplasm {ECO:0000255|HAMAP- Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cell projection {ECO:0000269|PubMed:19620624}. Note=Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.
Top Pathways	Cysteine and methionine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MGC3207 293T Cell Transient Overexpression Lysate(Denatured) - H00084245-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

MRI1 overexpression lysate - LY422176 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MRI1 293 Cell Lysate - 405267 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MRI1 293 Cell Lysate - 409660 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

EI2BL Overexpression Lysate (Native) - NBL1-13065 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MRI1 Over-expression Lysate Product - GWB-F6759F from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

MRI1 Over-expression Lysate Product - GWB-E0968D from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

EI2BL Overexpression Lysate (Denatured) - H00084245-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

EI2BL Overexpression Lysate (Denatured) - H00084245-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human MRI1 Knockdown Stable Cell Line - CSC-DC009715 from Creative biogene Category Cell Line Species Human

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