MRI1

Gene Symbol	MRI1
Entrez Gene	84245
Alt Symbol	MRDI, MTNA, Ypr118w
Species	Human
Gene Type	protein-coding
Description	methylthioribose-1-phosphate isomerase 1
Other Description	M1Pi|MTR-1-P isomerase|S-methyl-5-thioribose-1-phosphate isomerase 1|mediator of RhoA-dependent invasion|methylthioribose-1-phosphate isomerase|methylthioribose-1-phosphate isomerase homolog|translation initiation factor eIF-2B subunit alpha/beta/delta-like protein
Swissprots	Q8NDC9 Q9BV20
Accessions	EAW84369 EAW84370 EAW84371 Q9BV20 AF318324 AAL55831 AL834276 CAD38951 AM392616 CAL37494 AM393224 CAL38102 AY358176 AAQ88543 BC001703 AAH01703 BM147362 EU832338 ACE87595 EU832423 ACE86908 HQ448241 ADQ32721 XM_011528355 XP_011526657 XM_011528356 XP_011526658 XM_011528357 XP_011526659 XR_244089 NM_001031727 NP_001026897 NM_032285 NP_115661
Function	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover. {ECO:0000255|HAMAP-Rule:MF_03119, ECO:0000269|PubMed:19620624}.
Subcellular Location	Nucleus {ECO:0000255|HAMAP-Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cytoplasm {ECO:0000255|HAMAP- Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cell projection {ECO:0000269|PubMed:19620624}. Note=Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.
Top Pathways	Cysteine and methionine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EI2BL full length protein - ab164532 from Abcam Category Protein Source Wheat germ Species Human

MRI1 Antibody Blocking Peptide - LS-E22129 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MRI1 Antibody Blocking Peptide - LS-E22130 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MRI1 Antibody Blocking Peptide - LS-E13391 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MRI1 Antibody Blocking Peptide - LS-E13390 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EI2BL Recombinant Protein - H00084245-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MGC3207 Blocking Peptide - 33R-9710 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MGC3207 Blocking Peptide - 33R-1464 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MRI1 - H00084245-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MRI1 - H00084245-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MRI1 fusion protein - Ag13809 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human MRI1, GST-tagged - MRI1-972H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Methylthioribose-1-phosphate isomerase(mtnA) - CSB-YP885886XBL CSB-EP885886XBL CSB-BP885886XBL CSB-MP885886XBL from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Xylella

Recombinant Human Methylthioribose-1-phosphate isomerase(MRI1) - CSB-YP863127HU CSB-EP863127HU CSB-BP863127HU CSB-MP863127HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Methylthioribose-1-phosphate isomerase 1(mtnA1) - CSB-YP772373BQE CSB-EP772373BQE CSB-BP772373BQE CSB-MP772373BQE from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Bacillus

Recombinant Methylthioribose-1-phosphate isomerase(mtnA) - CSB-YP737826SRW CSB-EP737826SRW CSB-BP737826SRW CSB-MP737826SRW from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell

Recombinant Methylthioribose-1-phosphate isomerase(mtnA) - CSB-YP737710YAH CSB-EP737710YAH CSB-BP737710YAH CSB-MP737710YAH from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Yersinia

Recombinant Methylthioribose-1-phosphate isomerase(mtnA) - CSB-YP691898XBB CSB-EP691898XBB CSB-BP691898XBB CSB-MP691898XBB from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Xanthomonas

Recombinant Methylthioribose-1-phosphate isomerase(LmjF36.4930, LmjF_36_4930) - CSB-YP683862LOG CSB-EP683862LOG CSB-BP683862LOG CSB-MP683862LOG from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Leishmania

Recombinant Methylthioribose-1-phosphate isomerase (CBG11572) - CSB-YP014799CXX CSB-EP014799CXX CSB-BP014799CXX CSB-MP014799CXX from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Caenorhabditis

Recombinant Methylthioribose-1-phosphate isomerase(mtnA) - CSB-YP014799MOA CSB-EP014799MOA CSB-BP014799MOA CSB-MP014799MOA from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell

Recombinant Methylthioribose-1-phosphate isomerase (LinJ36.0740, LinJ_36_5160) - CSB-YP014799LOF CSB-EP014799LOF CSB-BP014799LOF CSB-MP014799LOF from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Leishmania

MRI1 (transcript variant 1) - TP300993 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

EI2BL Recombinant Protein Antigen - NBP2-47475PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MRI1-Blocking-Peptide-Center - BP22034c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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