SAMHD1

Gene Symbol	SAMHD1
Entrez Gene	25939
Alt Symbol	CHBL2, DCIP, HDDC1, MOP-5, SBBI88
Species	Human
Gene Type	protein-coding
Description	SAM domain and HD domain 1
Other Description	SAM domain and HD domain-containing protein 1|dNTPase|dendritic cell-derived IFNG-induced protein|deoxynucleoside triphosphate triphosphohydrolase SAMHD1|monocyte protein 5
Swissprots	Q9Y3Z3 Q9H005 E1P5V2 Q5JXG8 Q9H004 Q9H3U9 B4E2A5 Q8N491
Accessions	EAW76090 EAW76091 Q9Y3Z3 AB013847 BAB18916 AB208944 BAD92181 AF228421 AAF32407 AK027811 BAB55386 AK304187 BAG65067 AK304795 BAG65545 AK311150 AK315169 AL050267 CAB43368 BC036450 AAH36450 CA392465 DA351335 JF432320 ADZ15537 XM_005260384 XP_005260441 XM_011528761 XP_011527063 NM_015474 NP_056289
Function	Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling. {ECO:0000269|PubMed:18546154, ECO:0000269|PubMed:19525956, ECO:0000269|PubMed:22056990, ECO:0000269|PubMed:24336198}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:19525956, ECO:0000269|PubMed:23092512}.
Tissue Specificity	Expressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes. No expression is seen in brain and thymus. {ECO:0000269|PubMed:11064105}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SAM domain and HD domain-containing protein 1 (SAMHD1), Human, ELISA Kit - CSB-EL020691HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

SAM domain and HD domain-containing protein 1 (SAMHD1), Human, ELISA Kit - E01S0349 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

SAMHD1 (Human) IP-WB Antibody Pair - H00025939-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

SAM domain and HD domain 1, ELISA Kit - MBS943731 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human SAMHD1 is typically less than 5.86 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 23.44 pg/ml -1500 pg/ml.

Human SAM domain and HD domain-containing protein 1(SAMHD1) ELISA kit - CSB-EL020691HU from Cusabio Category ELISA Kit Sensitivity 5.8 pg/ml Range 23.44 pg/ml-1500 pg/ml

Human SAMHD1 ELISA Kit - E034216 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human SAMHD1 is typically less than 5.86 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the m

SAMHD1 ELISA Kit (Human) (OKCA01499) - OKCA01499 from Aviva Systems Biology Category ELISA Kit Prices $600.00 Sizes 96 wells Sensitivity 5.8 pg/mL Range 23.44 - 1,500 pg/mL

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