SAMHD1

Gene Symbol	SAMHD1
Entrez Gene	25939
Alt Symbol	CHBL2, DCIP, HDDC1, MOP-5, SBBI88
Species	Human
Gene Type	protein-coding
Description	SAM domain and HD domain 1
Other Description	SAM domain and HD domain-containing protein 1|dNTPase|dendritic cell-derived IFNG-induced protein|deoxynucleoside triphosphate triphosphohydrolase SAMHD1|monocyte protein 5
Swissprots	Q9Y3Z3 Q9H005 E1P5V2 Q5JXG8 Q9H004 Q9H3U9 B4E2A5 Q8N491
Accessions	EAW76090 EAW76091 Q9Y3Z3 AB013847 BAB18916 AB208944 BAD92181 AF228421 AAF32407 AK027811 BAB55386 AK304187 BAG65067 AK304795 BAG65545 AK311150 AK315169 AL050267 CAB43368 BC036450 AAH36450 CA392465 DA351335 JF432320 ADZ15537 XM_005260384 XP_005260441 XM_011528761 XP_011527063 NM_015474 NP_056289
Function	Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling. {ECO:0000269|PubMed:18546154, ECO:0000269|PubMed:19525956, ECO:0000269|PubMed:22056990, ECO:0000269|PubMed:24336198}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:19525956, ECO:0000269|PubMed:23092512}.
Tissue Specificity	Expressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes. No expression is seen in brain and thymus. {ECO:0000269|PubMed:11064105}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SAMHD1 full length protein - ab153254 from Abcam Category Protein Source Wheat germ Species Human

SAMHD1 Antibody Blocking Peptide - LS-E5142 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SAMHD1 Antibody Blocking Peptide - LS-E19950 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SAMHD1 Recombinant Protein - H00025939-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

SAMHD1-Antibody-Center-Blocking-Peptide - BP17570c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SAMHD1 Blocking Peptide - 33R-4405 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SAMHD1 - H00025939-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SAMHD1 - H00025939-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SAMHD1 (phospho Thr592) Peptide - 8005P from ProSci Category Peptide Species Human

SAMHD1 Peptide - 8007P from ProSci Category Peptide Species Human

SAMHD1 fusion protein - Ag3287 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

SAMHD1 fusion protein - Ag18766 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human SAMHD1, GST-tagged - SAMHD1-2505H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human SAM domain and HD domain-containing protein 1(SAMHD1) - CSB-YP896510HU CSB-EP896510HU CSB-BP896510HU CSB-MP896510HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SAMHD1 Protein - abx164551 from Abbexa Category Protein Species Human

SAMHD1 - TP306013 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SAMHD1 Recombinant Protein Antigen - NBP2-47292PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SAMHD1 Peptide, Human - M34GP13773H from Creative Peptides Category Peptide Source Synthetic. Species Human

SAM domain and HD domain-containing protein 1 (SAMHD1), Recombinant Protein - MBS1305340 from MyBioSource Category Protein Prices $1,420.00, $1,420.00, $1,650.00, $1,650.00, $2,405.00, $2,405.00, $2,850.00, $2,850.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more