SAMHD1

Gene Symbol	SAMHD1
Entrez Gene	25939
Alt Symbol	CHBL2, DCIP, HDDC1, MOP-5, SBBI88
Species	Human
Gene Type	protein-coding
Description	SAM domain and HD domain 1
Other Description	SAM domain and HD domain-containing protein 1|dNTPase|dendritic cell-derived IFNG-induced protein|deoxynucleoside triphosphate triphosphohydrolase SAMHD1|monocyte protein 5
Swissprots	Q9Y3Z3 Q9H005 E1P5V2 Q5JXG8 Q9H004 Q9H3U9 B4E2A5 Q8N491
Accessions	EAW76090 EAW76091 Q9Y3Z3 AB013847 BAB18916 AB208944 BAD92181 AF228421 AAF32407 AK027811 BAB55386 AK304187 BAG65067 AK304795 BAG65545 AK311150 AK315169 AL050267 CAB43368 BC036450 AAH36450 CA392465 DA351335 JF432320 ADZ15537 XM_005260384 XP_005260441 XM_011528761 XP_011527063 NM_015474 NP_056289
Function	Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling. {ECO:0000269|PubMed:18546154, ECO:0000269|PubMed:19525956, ECO:0000269|PubMed:22056990, ECO:0000269|PubMed:24336198}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:19525956, ECO:0000269|PubMed:23092512}.
Tissue Specificity	Expressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes. No expression is seen in brain and thymus. {ECO:0000269|PubMed:11064105}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-SAMHD1-cDNA-Clone - DC07043 from Abgent, a WuXi AppTec company Prices $845.10 Sizes 10 µg Species Human Accession BC036450

SAMHD1 - MBS1276663 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC036450

Human SAMHD1 ORF clone(NM_015474.3) - CDCL186057 from Creative Biomart Species Human Accession NM_015474.3

Human SAMHD1 ORF Clone(NM_015474.3) - CDCL174526 from Creative Biomart Species Human Accession NM_015474.3

Human SAMHD1 Gene cDNA clone plasmid - HG13780-G from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13780-ANG from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13780-NY from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13780-ACG from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13780-NF from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG13780-ANR from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13780-NM from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13780-CF from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13780-CM from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid, N-His tag - HG13780-NH from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13780-CY from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid - HG13780-UT from Sino Biological Species Human

Human SAMHD1 Gene ORF cDNA clone expression plasmid, C-His tag - HG13780-CH from Sino Biological Species Human

Human SAMHD1 ORF clone(NM_015474.3) - CDCL186057 from Creative biogene Species Human

Human SAMHD1 ORF Clone (BC036450) - CDCS413975 from Creative biogene Species Human Accession Q9Y3Z3

Human SAMHD1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13780-ACR from Sino Biological Species Human

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