KARS

Gene Symbol	KARS
Entrez Gene	3735
Alt Symbol	CMTRIB, DFNB89, KARS1, KARS2, KRS
Species	Human
Gene Type	protein-coding
Description	lysyl-tRNA synthetase
Other Description	lysRS|lysine tRNA ligase|lysine--tRNA ligase
Swissprots	D3DUK4 Q96J25 O14946 Q9HB23 Q15046 A8MSK1
Accessions	EAW95619 EAW95620 EAW95621 EAW95622 EAW95623 EAW95624 Q15046 AA503390 AF285758 AAG30114 AK126584 BAC86604 AK309168 AK315687 BC004132 AAH04132 BC013246 BM781594 D31890 BAA06688 D32053 BAA22084 DQ892301 ABM83227 DQ895500 ABM86426 NM_001130089 NP_001123561 NM_005548 NP_005539
Function	Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA(3)(Lys), the primer for reverse transcription initiation. {ECO:0000269|PubMed:15851690, ECO:0000269|PubMed:5338216}.
Subcellular Location	Isoform Cytoplasmic: Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Secreted. Note=Secretion is induced by TNF-alpha.
Top Pathways	Aminoacyl-tRNA biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KARS - MBS1266409 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC004132

Human KARS cDNA clone(NM_001130089.1) - CDFH009561 from Creative Biomart Species Human Accession NM_001130089.1

Human KARS ORF Clone(NM_001130089.1) - CDCR349452 from Creative Biomart Species Human Accession NM_001130089.1

Human KARS ORF Clone(NM_001130089.1) - CDCR349453 from Creative Biomart Species Human Accession NM_001130089.1

Human KARS ORF Clone(NM_005548.2) - CDCL167627 from Creative Biomart Species Human Accession NM_005548.2

Human KARS ORF Clone(NM_001130089.1) - CDCL167628 from Creative Biomart Species Human Accession NM_001130089.1

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone in cloning vector - HG14355-G from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14355-CM from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, N-His tag - HG14355-NH from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14355-ANG from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14355-ACG from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, N-HA tag - HG14355-NY from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, C-His tag - HG14355-CH from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid - HG14355-UT from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, C-HA tag - HG14355-CY from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14355-NF from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14355-CF from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14355-NM from Sino Biological Species Human

Human KARS ORF clone (NM_001130089.1) - CDCL122575 from Creative biogene Species Human

Human KARS ORF Clone (BC004132) - CDCS407910 from Creative biogene Species Human Accession Q15046

Human KARS ORF clone (BC004132) - CDCB159148 from Creative biogene Species Human

Human KARS cDNA Clone(NM_001130089.1) - CDFH009561 from Creative biogene Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14355-ACR from Sino Biological Species Human

Human LysRS/Lysyl tRNA synthetase Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14355-ANR from Sino Biological Species Human

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