U2AF2

Gene Symbol U2AF2
Entrez Gene 11338
Alt Symbol U2AF65
Species Human
Gene Type protein-coding
Description U2 small nuclear RNA auxiliary factor 2
Other Description U2 (RNU2) small nuclear RNA auxiliary factor 2|U2 auxiliary factor 65 kDa subunit|U2 small nuclear ribonucleoprotein auxiliary factor (65kD)|U2 snRNP auxiliary factor large subunit|hU2AF65|splicing factor U2AF 65 kDa subunit
Swissprots Q96HC5 P26368
Accessions EAW72402 EAW72403 EAW72404 P26368 AB451261 BAG70075 AB451387 BAG70201 AK311672 BC008740 AAH08740 BC030574 AAH30574 CN364862 DQ592840 JF432180 ADZ15397 X64044 CAA45409 XM_006722994 XP_006723057 XM_011526410 XP_011524712 NM_001012478 NP_001012496 NM_007279 NP_009210
Function Necessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10. {ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:19470458, ECO:0000269|PubMed:19574390, ECO:0000269|PubMed:21536736}.
Subcellular Location Nucleus.
Top Pathways Spliceosome

Human-U2AF2-cDNA-Clone - DC02472 from Abgent, a WuXi AppTec company

Prices $635.85
Sizes 10 µg
Species Human
Accession BC008740

U2AF2 - MBS1273243 from MyBioSource

Species Human
Accession BC008740

Human U2AF2 cDNA clone(NM_001012478.1) - CDFH020701 from Creative Biomart

Species Human
Accession NM_001012478.1

Human U2AF2 cDNA clone(NM_007279.2) - CDFH020702 from Creative Biomart

Species Human
Accession NM_007279.2

Human U2AF2 ORF Clone(NM_007279.2) - CDCR294786 from Creative Biomart

Species Human
Accession NM_007279.2

Human U2AF2 ORF Clone(NM_007279.2) - CDCR294787 from Creative Biomart

Species Human
Accession NM_007279.2

Human U2AF2 ORF Clone(NM_001012478.1) - CDCR341193 from Creative Biomart

Species Human
Accession NM_001012478.1

Human U2AF2 ORF Clone(NM_001012478.1) - CDCR341194 from Creative Biomart

Species Human
Accession NM_001012478.1

human U2AF2 ORF clone - CDCH097156 from Creative Biomart

Species Human
Accession NM_001012478

human U2AF2 ORF clone - CDCH097157 from Creative Biomart

Species Human
Accession NM_001012478

human U2AF2 ORF clone - CDCH097158 from Creative Biomart

Species Human
Accession NM_001012478

human U2AF2 ORF clone - CDCH097159 from Creative Biomart

Species Human
Accession NM_001012478

Human U2AF2 ORF Clone(NM_007279.2) - CDCR294786 from Creative biogene

Species Human

Human U2AF2 ORF Clone(NM_001012478.1) - CDCR341193 from Creative biogene

Species Human

Human U2AF2 ORF Clone (BC008740) - CDCS406497 from Creative biogene

Species Human
Accession P26368

Human U2AF2 cDNA Clone(NM_001012478.1) - CDFH020701 from Creative biogene

Species Human

Human U2AF2 cDNA Clone(NM_007279.2) - CDFH020702 from Creative biogene

Species Human
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