U2AF2

Gene Symbol	U2AF2
Entrez Gene	11338
Alt Symbol	U2AF65
Species	Human
Gene Type	protein-coding
Description	U2 small nuclear RNA auxiliary factor 2
Other Description	U2 (RNU2) small nuclear RNA auxiliary factor 2|U2 auxiliary factor 65 kDa subunit|U2 small nuclear ribonucleoprotein auxiliary factor (65kD)|U2 snRNP auxiliary factor large subunit|hU2AF65|splicing factor U2AF 65 kDa subunit
Swissprots	Q96HC5 P26368
Accessions	EAW72402 EAW72403 EAW72404 P26368 AB451261 BAG70075 AB451387 BAG70201 AK311672 BC008740 AAH08740 BC030574 AAH30574 CN364862 DQ592840 JF432180 ADZ15397 X64044 CAA45409 XM_006722994 XP_006723057 XM_011526410 XP_011524712 NM_001012478 NP_001012496 NM_007279 NP_009210
Function	Necessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10. {ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:19470458, ECO:0000269|PubMed:19574390, ECO:0000269|PubMed:21536736}.
Subcellular Location	Nucleus.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human U2AF65 peptide - ab37528 from Abcam Category Peptide

Human U2AF65 peptide - ab37529 from Abcam Category Peptide

Human U2AF65 protein fragment - ab153184 from Abcam Category Protein Source Wheat germ Species Human

U2AF2 / U2AF65 Antibody Blocking Peptide - LS-E3407 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

U2AF2 / U2AF65 Antibody Blocking Peptide - LS-E14673 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

U2AF2 / U2AF65 Antibody Blocking Peptide - LS-E14674 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

U2AF2 Partial Recombinant Protein - H00011338-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

U2AF2-Antibody-N-term-Blocking-Peptide - BP14583a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

U2AF2 Blocking Peptide - 33R-2401 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

U2AF2 / U2AF65 - H00011338-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

U2AF2 / U2AF65 - H00011338-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

U2AF2 fusion protein - Ag8070 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human U2AF2, GST-tagged - U2AF2-3513H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Splicing factor U2AF 65 kDa subunit(uaf-1) - CSB-YP025408CXX CSB-EP025408CXX CSB-BP025408CXX CSB-MP025408CXX from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Caenorhabditis

Recombinant Human Splicing factor U2AF 65 kDa subunit(U2AF2) - CSB-YP025408HU CSB-EP025408HU CSB-BP025408HU CSB-MP025408HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

U2AF2 Recombinant Protein Antigen - NBP2-33397PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

U2AF2 Peptide, Human - M34GP16924H from Creative Peptides Category Peptide Source Synthetic. Species Human

U2AF2 Recombinant Protein Antigen - NBP2-58989PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

Splicing factor U2AF 65 kDa subunit (U2AF2), Recombinant Protein - MBS962118 from MyBioSource Category Protein Prices $1,720.00, $1,875.00, $2,030.00, $2,145.00, $2,340.00, $2,375.00, $2,680.00, $2,940.00, $3,395.00, $4,235.00 Sizes 50 µg (Baculovirus), 500 µg (E-Coli), 500 µg (Yeast), 100 µg (Baculovirus), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 1 mg (Yeast), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Splicing factor U2AF 65 kDa subunit (uaf-1), Recombinant Protein - MBS1264164 from MyBioSource Category Protein Prices $1,275.00, $1,275.00, $1,495.00, $1,495.00, $2,085.00, $2,085.00, $2,550.00, $2,550.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Caenorhabditis

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