THAP1

Gene Symbol THAP1
Entrez Gene 55145
Alt Symbol DYT6
Species Human
Gene Type protein-coding
Description THAP domain containing, apoptosis associated protein 1
Other Description 4833431A01Rik|THAP domain protein 1|THAP domain-containing protein 1|nuclear proapoptotic factor
Swissprots H9KV49 Q6IA99 Q53FQ1 D3DSY5 A6NCB6 Q9NVV9
Accessions EAW63205 EAW63206 Q9NVV9 AI475984 AK001339 BAA91635 AK223231 BAD96951 AL832077 BC021721 AAH21721 BG497522 CD639319 CD709111 CR457256 CAG33537 JF432589 ADZ15806 NM_018105 NP_060575 NM_199003 NP_945354
Function DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis. {ECO:0000269|PubMed:12717420, ECO:0000269|PubMed:17003378, ECO:0000269|PubMed:20200153}.
Subcellular Location Nucleus, nucleoplasm {ECO:0000269|PubMed:12717420}. Nucleus, PML body {ECO:0000269|PubMed:12717420}.
Tissue Specificity Highly expressed in heart, skeletal muscle, kidney and liver. Weaker expression in brain and placenta. {ECO:0000269|PubMed:20200153}.

Human-THAP1-cDNA-Clone - DC05133 from Abgent, a WuXi AppTec company

Prices $287.55
Sizes 10 µg
Species Human
Accession BC021721

THAP1 - MBS1278737 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC021721

Human THAP1 cDNA clone(NM_018105.2) - CDFG001433 from Creative Biomart

Species Human
Accession NM_018105.2

Human THAP1 cDNA clone(NM_018105.2) - CDFG001434 from Creative Biomart

Species Human
Accession NM_018105.2

Human THAP1 cDNA clone(NM_199003.1) - CDFG013029 from Creative Biomart

Species Human
Accession NM_199003.1

Human THAP1 ORF Clone(NM_018105.2) - CDCL178371 from Creative Biomart

Species Human
Accession NM_018105.2

Human THAP1 ORF Clone(NM_018105.2) - CDCR303069 from Creative Biomart

Species Human
Accession NM_018105.2

Human THAP1 ORF Clone(NM_018105.2) - CDCR303070 from Creative Biomart

Species Human
Accession NM_018105.2

Human THAP1 ORF Clone(NM_018105.2) - CDCR303071 from Creative Biomart

Species Human
Accession NM_018105.2

Human THAP1 ORF Clone(NM_199003.1) - CDCR326471 from Creative Biomart

Species Human
Accession NM_199003.1

Human THAP1 ORF Clone(NM_199003.1) - CDCR326472 from Creative Biomart

Species Human
Accession NM_199003.1

human THAP1 ORF clone - CDCH090722 from Creative Biomart

Species Human

human THAP1 ORF clone - CDCH090723 from Creative Biomart

Species Human

human THAP1 ORF clone - CDCH090724 from Creative Biomart

Species Human

human THAP1 ORF clone - CDCH090725 from Creative Biomart

Species Human

Human THAP1 ORF Clone(NM_018105.2) - CDCR303069 from Creative biogene

Species Human

human THAP1 ORF clone (NM_199003.1) - CDCH090724 from Creative biogene

Species Human

Human THAP1 ORF Clone (BC021721) - CDCS419731 from Creative biogene

Species Human
Accession Q9NVV9

Human THAP1 cDNA Clone(NM_018105.2) - CDFG001433 from Creative biogene

Species Human

Human THAP1 cDNA Clone(NM_018105.2) - CDFG001434 from Creative biogene

Species Human

Human THAP1 cDNA Clone(NM_199003.1) - CDFG013029 from Creative biogene

Species Human
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