THAP1

Gene Symbol	THAP1
Entrez Gene	55145
Alt Symbol	DYT6
Species	Human
Gene Type	protein-coding
Description	THAP domain containing, apoptosis associated protein 1
Other Description	4833431A01Rik|THAP domain protein 1|THAP domain-containing protein 1|nuclear proapoptotic factor
Swissprots	H9KV49 Q6IA99 Q53FQ1 D3DSY5 A6NCB6 Q9NVV9
Accessions	EAW63205 EAW63206 Q9NVV9 AI475984 AK001339 BAA91635 AK223231 BAD96951 AL832077 BC021721 AAH21721 BG497522 CD639319 CD709111 CR457256 CAG33537 JF432589 ADZ15806 NM_018105 NP_060575 NM_199003 NP_945354
Function	DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis. {ECO:0000269|PubMed:12717420, ECO:0000269|PubMed:17003378, ECO:0000269|PubMed:20200153}.
Subcellular Location	Nucleus, nucleoplasm {ECO:0000269|PubMed:12717420}. Nucleus, PML body {ECO:0000269|PubMed:12717420}.
Tissue Specificity	Highly expressed in heart, skeletal muscle, kidney and liver. Weaker expression in brain and placenta. {ECO:0000269|PubMed:20200153}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human THAP1 full length protein - ab124553 from Abcam Category Protein Source E. coli Species Human

THAP1 Recombinant Protein - H00055145-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human THAP1 Protein - NBP1-99010 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 100 µg, 500 µg Source E.coli Species Human

Human THAP1 protein - orb169423 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 5 μg, 20 μg Source E. coli Species Human

THAP1 protein (His tag) - 80R-2257 from Fitzgerald Category Protein Prices $365.00 Sizes 100 µg Source E.coli

THAP1 (1-213, His-tag) - AR50341PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 500 µg Source E. coli Species Human

THAP1 (1-213, His-tag) - AR50341PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

THAP1 - H00055145-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

THAP1 - H00055145-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

THAP1, 1-213 aa, Human, His tag, E.coli - 01-P1517 from ARP American Research Products Category Protein Prices $189.00, $449.00, $1,089.00 Sizes 20 µg, 50 µg, 500 µg Species Human

THAP1 fusion protein - Ag3285 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

THAP1 Human - PRPS-1096 from NeoScientific Category Protein Prices $65.00, $169.00, $4,680.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

THAP1, 1-213 aa , Human, His tag, E.coli - GWB-P0521A from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human THAP Domain Containing, Apoptosis Associated Protein 1, His-tagged - THAP1-5594H from Creative Biomart Category Protein

Recombinant Human THAP1, His-tagged - THAP1-15857H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human THAP1, GST-tagged - THAP1-3213H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human THAP domain-containing protein 1(THAP1) - CSB-YP885741HU CSB-EP885741HU CSB-BP885741HU CSB-MP885741HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

THAP1, 1-213aa, Human, His tag, E.coli (Denatured) - ATGP1517 from ATGen Category Protein Prices $105.00, $320.00, $960.00 Sizes 20 µg, 100 µg, 500 µg Species Human

THAP1 Protein - abx164376 from Abbexa Category Protein Species Human, Mouse, Rat

THAP1 (transcript variant 1) - TP306000 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

THAP Domain Containing, Recombinant Protein - MBS144781 from MyBioSource Category Protein Prices $140.00, $205.00, $3,515.00 Sizes 5 µg, 20 µg, 1 mg Source E Coli

THAP domain-containing protein 1 (THAP1), Recombinant Protein - MBS1426054 from MyBioSource Category Protein Prices $965.00, $965.00, $1,185.00, $1,185.00, $1,445.00, $1,445.00, $1,910.00, $1,910.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

THAP1, Recombinant Protein - MBS204170 from MyBioSource Category Protein Prices $375.00, $925.00 Sizes 100 µg, 500 µg Source E Coli Species Human

THAP1 fusion protein - Ag25305 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

THAP1 Peptide, Human - M34GP15887H from Creative Peptides Category Peptide Source Synthetic. Species Human

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