SLC22A2

Gene Symbol	SLC22A2
Entrez Gene	6582
Alt Symbol	OCT2
Species	Human
Gene Type	protein-coding
Description	solute carrier family 22 (organic cation transporter), member 2
Other Description	organic cation transporter 2|solute carrier family 22 member 2
Swissprots	Q6PIQ8 Q9NQB9 Q5T7Q6 O15244 Q8NG62
Accessions	CAB96133 EAW47601 EAW47602 O15244 AB075951 BAC02720 AK290787 BAF83476 BC030978 AAH30978 BC039899 AAH39899 X98333 CAA66978 NM_003058 NP_003049 NM_153191
Function	Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity. {ECO:0000269|PubMed:12089365, ECO:0000269|PubMed:12538837, ECO:0000269|PubMed:15496291, ECO:0000269|PubMed:15783073, ECO:0000269|PubMed:16006492, ECO:0000269|PubMed:16272756, ECO:0000269|PubMed:16314463, ECO:0000269|PubMed:16394027, ECO:0000269|PubMed:16914559, ECO:0000269|PubMed:16951202, ECO:0000269
Subcellular Location	Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity	Mainly expressed in kidney. Localized at the luminal membrane and basolateral membrane of kidney distal tubule and proximal tubules. To a lower extent, expressed in neurons of the cerebral cortex and in various subcortical nuclei (at protein levels). Also detected in secretory phase endometrium; in scattered cells in the stroma. {ECO:0000269|PubMed:11912245, ECO:0000269|PubMed:17393420, ECO:0000269|PubMed:9260930, ECO:0000269|PubMed:9687576}.
Top Pathways	Choline metabolism in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

solute carrier family 22 (organic cation transporter) , member 2, ELISA Kit - MBS9327905 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human OCT2(Octamer-binding protein 2) ELISA Kit - E-EL-H1021 from Elabscience Category ELISA Kit Sensitivity 9.38 pg/mL Range 15.63—1000 pg/mL

Human OCT2(Octamer-binding protein 2) ELISA Kit - E-EL-H1021 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 9.38 pg/mLpg/mL Range 15.63~1000 pg/mL

OCT2 ELISA Kit - DEIA-XYA1356 from Creative Diagnostics Category ELISA Kit

OCT2 ELISA Kit - DEIA-XYA1357 from Creative Diagnostics Category ELISA Kit

Human OCT2 ELISA Kit - E027233 from Biobool Category ELISA Kit

Human SLC22A2 ELISA Kit - E035928 from Biobool Category ELISA Kit

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9353908 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9344504 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9368986 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9344851 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9365305 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9356765 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9349093 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9349423 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9345518 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9358756 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9348524 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9345042 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9350508 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9359198 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9363628 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9360576 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9351625 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 2 (SLC22A2), ELISA Kit - MBS9379828 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more