GNL3

Gene Symbol GNL3
Entrez Gene 26354
Alt Symbol C77032, E2IG3, NNP47, NS
Species Human
Gene Type protein-coding
Description guanine nucleotide binding protein-like 3 (nucleolar)
Other Description E2-induced gene 3 protein|estradiol-induced nucleotide binding protein|guanine nucleotide-binding protein-like 3|novel nucleolar protein 47|nucleolar GTP-binding protein 3|nucleostemin
Swissprots Q96SV7 B2RDC1 Q9UJY0 Q96SV6 Q5PU80 Q9BVP2
Accessions EAW65249 EAW65250 EAW65251 EAW65252 Q9BVP2 AF191018 AAF09482 AI028402 AK027514 BAB55168 AK027516 BAB55169 AK315484 BAG37868 AY825265 AAV74413 BC001024 AAH01024 BF732788 CF272475 EU831969 ACE87410 EU832062 ACE86724 NM_014366 NP_055181 NM_206825 NP_996561 NM_206826 NP_996562
Function May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250}.
Tissue Specificity Increased levels in lung tissue in cancer patients. {ECO:0000269|PubMed:16012751}.
Top Pathways Ribosome biogenesis in eukaryotes

Nucleostemin Antibody - 9495 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Nucleostemin Antibody.

Nucleostemin (E-8) - sc-166460 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nucleostemin (E-8): sc-166460. Western blot analysis of Nucleostemin expression in SW480 (A) and K-562 (B) nuclear extracts.

Nucleostemin (F-5) - sc-398978 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nucleostemin (F-5): sc-398978. Western blot analysis of Nucleostemin expression in HeLa (A) and SW480 (B) nuclear extracts.

Nucleostemin (A-8) - sc-166430 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nucleostemin (A-8): sc-166430. Western blot analysis of Nucleostemin expression in LADMAC whole cell lysate.

Nucleostemin (M-270) - sc-67013 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Nucleostemin (M-270): sc-67013. Western blot analysis of Nucleostemin expression in LADMAC whole cell lysate.

Nucleostemin (C-14) - sc-46212 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
donkey anti-goat IgG-CFL 405 sc-362245. Immunofluorescence staining of formalin-fixed HepG2 cells showing nucleolar and nuclear localization. Antibody tested: Nucleostemin (C-14): sc-46212. Donkey anti-goat IgG was conjugated to CruzFluor&rade; 405 succinimidyl ester: sc-362616.

Nucleostemin (H-270) - sc-67012 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Nucleostemin (H-270): sc-67012. Western blot analysis of Nucleostemin expression in 293T whole cell lysate.

Nucleostemin (E-19) - sc-46215 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nucleostemin (E-19): sc-46215. Western blot analysis of Nucleostemin expression in Hep G2 (A), SW480 (B), K-562 (C) and HEL 92.1.7 (D) nuclear extracts.

Nucleostemin (P-19) - sc-46219 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nucleostemin (P-19): sc-46219. Western blot analysis of Nucleostemin expression in HeLa (A), Hep G2 (B) and LADMAC (C) nuclear extracts.

Nucleostemin (P-13) - sc-46218 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nucleostemin (P-13): sc-46218. Western blot analysis of Nucleostemin expression in Hep G2 (A) and SW480 (B) nuclear extracts.

Anti-GNL3 / NS / Nucleostemin Antibody (aa1-226, clone 2C8D5) - LS-C191783 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C8D5
Western blot using GNL3 monoclonal antibody against HEK293 (1) and GNL3 (AA: 1-226)-hIgGFc transfected HEK293 (2) cell lysate.

Anti-GNL3 / NS / Nucleostemin Antibody (aa1-226, clone 2C8D5) - LS-C191782 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C8D5
Western blot using GNL3 monoclonal antibody against HEK293 (1) and GNL3 (AA: 1-226)-hIgGFc transfected HEK293 (2) cell lysate.

Anti-GNL3 / NS / Nucleostemin Antibody (aa1-280) - LS-C65141 from LifeSpan Bioscience

Prices $665.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-GNL3 / NS / Nucleostemin Antibody (aa1-50) - LS-C124946 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-GNL3 / NS / Nucleostemin Antibody (C-Terminus) - LS-C124947 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-GNL3 / NS / Nucleostemin Antibody (aa442-471, AP) - LS-C235823 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNL3 / NS / Nucleostemin Antibody (aa442-471, APC) - LS-C235824 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNL3 / NS / Nucleostemin Antibody (aa442-471, Biotin) - LS-C235825 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNL3 / NS / Nucleostemin Antibody (aa467-516) - LS-C108031 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GNL3 / Nucleostemin antibody LS-C108031 Western blot of 721_B cell lysate.

Anti-GNL3 / NS / Nucleostemin Antibody (N-Terminus) - LS-C112263 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GNL3 / Nucleostemin antibody LS-C112263 Western blot of Fetal Stomach lysate.

Anti-GNL3 / NS / Nucleostemin Antibody (aa442-471, PE) - LS-C235829 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNL3 / NS / Nucleostemin Antibody (aa442-471, FITC) - LS-C235826 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNL3 / NS / Nucleostemin Antibody (aa442-471, Azide-free, HRP) - LS-C249098 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNL3 / NS / Nucleostemin Antibody (aa191-220) - LS-C98100 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-GNL3 Antibody (RB13797) in HL60 cell line lysates (35 ug/lane). GNL3 (arrow) was detected using the purified antibody.

Anti-GNL3 / NS / Nucleostemin Antibody - LS-C307339 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
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