GNL3

Gene Symbol	GNL3
Entrez Gene	26354
Alt Symbol	C77032, E2IG3, NNP47, NS
Species	Human
Gene Type	protein-coding
Description	guanine nucleotide binding protein-like 3 (nucleolar)
Other Description	E2-induced gene 3 protein|estradiol-induced nucleotide binding protein|guanine nucleotide-binding protein-like 3|novel nucleolar protein 47|nucleolar GTP-binding protein 3|nucleostemin
Swissprots	Q96SV7 B2RDC1 Q9UJY0 Q96SV6 Q5PU80 Q9BVP2
Accessions	EAW65249 EAW65250 EAW65251 EAW65252 Q9BVP2 AF191018 AAF09482 AI028402 AK027514 BAB55168 AK027516 BAB55169 AK315484 BAG37868 AY825265 AAV74413 BC001024 AAH01024 BF732788 CF272475 EU831969 ACE87410 EU832062 ACE86724 NM_014366 NP_055181 NM_206825 NP_996561 NM_206826 NP_996562
Function	May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250}.
Tissue Specificity	Increased levels in lung tissue in cancer patients. {ECO:0000269|PubMed:16012751}.
Top Pathways	Ribosome biogenesis in eukaryotes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Nucleostemin CRISPR/Cas9 KO Plasmid (h) - sc-402271 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Nucleostemin HDR Plasmid (h) - sc-402271-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Nucleostemin Double Nickase Plasmid (h) - sc-402271-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Nucleostemin Double Nickase Plasmid (h2) - sc-402271-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Nucleostemin CRISPR Activation Plasmid (h) - sc-402271-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Nucleostemin CRISPR Activation Plasmid (h2) - sc-402271-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Nucleostemin Lentiviral Activation Particles (h) - sc-402271-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Nucleostemin Lentiviral Activation Particles (h2) - sc-402271-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Nucleostemin siRNA (h) - sc-45830 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Nucleostemin shRNA Plasmid (h) - sc-45830-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Nucleostemin shRNA (h) Lentiviral Particles - sc-45830-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Nucleostemin RNAi - H00026354-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Nucleostemin RNAi - H00026354-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU085631 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9437 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9437 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

GNL3 siRNA (Human) - CRH8821 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Nucleostemin RNAi - H00026354-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

GNL3 - MBS8233994 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human GNL3 (NM_014366.4) - SHH304994 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human GNL3(NM_014366.4) - SHH093115 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human GNL3(NM_206825.1) - SHH093161 from Creative biogene Category siRNA Species Reactivities Human

GNL3 shRNA Plasmid (Human) - CHH8821 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

GNL3 miRNA 3'UTR clone - MiUTR1H-04118 from Creative biogene Species Reactivities Human

GNL3 miRNA 3'UTR clone - MiUTR1H-04119 from Creative biogene Species Reactivities Human

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