Gene Symbol | GNL3 |
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Entrez Gene | 26354 |
Alt Symbol | C77032, E2IG3, NNP47, NS |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein-like 3 (nucleolar) |
Other Description | E2-induced gene 3 protein|estradiol-induced nucleotide binding protein|guanine nucleotide-binding protein-like 3|novel nucleolar protein 47|nucleolar GTP-binding protein 3|nucleostemin |
Swissprots | Q96SV7 B2RDC1 Q9UJY0 Q96SV6 Q5PU80 Q9BVP2 |
Accessions | EAW65249 EAW65250 EAW65251 EAW65252 Q9BVP2 AF191018 AAF09482 AI028402 AK027514 BAB55168 AK027516 BAB55169 AK315484 BAG37868 AY825265 AAV74413 BC001024 AAH01024 BF732788 CF272475 EU831969 ACE87410 EU832062 ACE86724 NM_014366 NP_055181 NM_206825 NP_996561 NM_206826 NP_996562 |
Function | May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250}. |
Tissue Specificity | Increased levels in lung tissue in cancer patients. {ECO:0000269|PubMed:16012751}. |
Top Pathways | Ribosome biogenesis in eukaryotes |
GNL3-Over-expression-Lysate - LY11048a from Abgent, a WuXi AppTec company
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GNL3 293T Cell Transient Overexpression Lysate(Denatured) - H00026354-T01 from Acris Antibodies
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GNL3 overexpression lysate - LY404228 from Acris Antibodies
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GNL3 overexpression lysate - LY415330 from Acris Antibodies
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GNL3 overexpression lysate - LY430949 from Acris Antibodies
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GNL3 293 Cell Lysate - 407221 from ABBIOTEC
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GNL3 293 Cell Lysate - 403302 from ABBIOTEC
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Nucleostemin Overexpression Lysate (Denatured) - H00026354-T01 from Novus Biologicals
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Nucleostemin Overexpression Lysate (Native) - NBL1-11183 from Novus Biologicals
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Nucleostemin Overexpression Lysate (Native) - NBL1-11182 from Novus Biologicals
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GNL3 Over-expression Lysate Product - GWB-CF737B from Genway Biotech
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GNL3 Over-expression Lysate Product - GWB-3D1271 from Genway Biotech
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Panoply™ Human GNL3 Knockdown Stable Cell Line - CSC-DC006415 from Creative biogene
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