Gene Symbol | GNL3 |
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Entrez Gene | 26354 |
Alt Symbol | C77032, E2IG3, NNP47, NS |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein-like 3 (nucleolar) |
Other Description | E2-induced gene 3 protein|estradiol-induced nucleotide binding protein|guanine nucleotide-binding protein-like 3|novel nucleolar protein 47|nucleolar GTP-binding protein 3|nucleostemin |
Swissprots | Q96SV7 B2RDC1 Q9UJY0 Q96SV6 Q5PU80 Q9BVP2 |
Accessions | EAW65249 EAW65250 EAW65251 EAW65252 Q9BVP2 AF191018 AAF09482 AI028402 AK027514 BAB55168 AK027516 BAB55169 AK315484 BAG37868 AY825265 AAV74413 BC001024 AAH01024 BF732788 CF272475 EU831969 ACE87410 EU832062 ACE86724 NM_014366 NP_055181 NM_206825 NP_996561 NM_206826 NP_996562 |
Function | May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250}. |
Tissue Specificity | Increased levels in lung tissue in cancer patients. {ECO:0000269|PubMed:16012751}. |
Top Pathways | Ribosome biogenesis in eukaryotes |
Human-GNL3-cDNA-Clone - DC00473 from Abgent, a WuXi AppTec company
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GNL3 - MBS1275892 from MyBioSource
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Human GNL3 cDNA clone(NM_206825.1) - CDFG013594 from Creative Biomart
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Human GNL3 cDNA clone(NM_206826.1) - CDFG013596 from Creative Biomart
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Human GNL3 cDNA clone(NM_014366.4) - CDFH007743 from Creative Biomart
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Human GNL3 ORF Clone(NM_014366.4) - CDCL164959 from Creative Biomart
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Human GNL3 ORF Clone(NM_014366.4) - CDCR297250 from Creative Biomart
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Human GNL3 ORF Clone(NM_014366.4) - CDCR297251 from Creative Biomart
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Human GNL3 ORF Clone(NM_014366.4) - CDCR297252 from Creative Biomart
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Human GNL3 ORF Clone(NM_206825.1) - CDCR327599 from Creative Biomart
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Human GNL3 ORF Clone(NM_206826.1) - CDCR327600 from Creative Biomart
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Human GNL3 ORF Clone(NM_206826.1) - CDCR327601 from Creative Biomart
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Human GNL3 ORF Clone(NM_206825.1) - CDCR327613 from Creative Biomart
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Human GNL3/Nucleostemin Gene ORF cDNA clone expression plasmid - HG12415-UT from Sino Biological
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Human GNL3 ORF Clone(NM_206825.1) - CDCR327599 from Creative biogene
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Mouse GNL3 ORF clone (NM_206826.1) - CDCL113209 from Creative biogene
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Mouse GNL3 ORF clone (NM_014366.4) - CDCL113211 from Creative biogene
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Human GNL3 ORF Clone (BC001024) - CDCS413597 from Creative biogene
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Human GNL3 cDNA Clone(NM_206825.1) - CDFG013594 from Creative biogene
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Human GNL3 cDNA Clone(NM_206826.1) - CDFG013596 from Creative biogene
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Human GNL3 cDNA Clone(NM_014366.4) - CDFH007743 from Creative biogene
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Human KRAS/K-RAS Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG12259-ANG from Sino Biological
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Human GNL3/Nucleostemin Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12415-ACG from Sino Biological
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Human GNL3/Nucleostemin Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12415-NF from Sino Biological
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Human GNL3/Nucleostemin Gene ORF cDNA clone expression plasmid, C-His tag - HG12415-CH from Sino Biological
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