UNC5C

Gene Symbol	UNC5C
Entrez Gene	8633
Alt Symbol	UNC5H3
Species	Human
Gene Type	protein-coding
Description	unc-5 homolog C (C. elegans)
Other Description	netrin receptor UNC5C|protein unc-5 homolog 3|protein unc-5 homolog C|unc-5 homolog 3|unc5 (C.elegans homolog) c
Swissprots	Q8IUT0 O95185
Accessions	AAY41022 EAX06061 EAX06062 O95185 AF055634 AAC67491 AK022487 AK290500 BAF83189 AK308421 BC034747 BC041156 AAH41156 BX538341 XM_005263321 XP_005263378 NM_003728 NP_003719
Function	Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity). {ECO:0000250}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Mainly expressed in brain. Also expressed in kidney. Not expressed in developing or adult lung. {ECO:0000269|PubMed:9782087}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

UNC5C - MBS1272613 from MyBioSource Species Human Accession BC041156

human UNC5C ORF clone - CDCH098256 from Creative Biomart Species Human Accession NM_003728

human UNC5C ORF clone - CDCH098257 from Creative Biomart Species Human Accession NM_003728

human UNC5C ORF clone - CDCH098258 from Creative Biomart Species Human Accession NM_003728

human UNC5C ORF clone - CDCH098259 from Creative Biomart Species Human Accession NM_003728

Human UNC5C ORF Clone(NM_003728.3) - CDCL180557 from Creative Biomart Species Human Accession NM_003728.3

Human UNC5C Gene ORF cDNA clone in cloning vector - HG13755-G from Sino Biological Species Human

Human UNC5C Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13755-NF from Sino Biological Species Human

Human UNC5C Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13755-NM from Sino Biological Species Human

Human UNC5C Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13755-CF from Sino Biological Species Human

Human UNC5C Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13755-CM from Sino Biological Species Human

Human UNC5C Gene ORF cDNA clone expression plasmid, N-His tag - HG13755-NH from Sino Biological Species Human

Human UNC5C Gene ORF cDNA clone expression plasmid, C-HA tag - HG13755-CY from Sino Biological Species Human

Human UNC5C Gene ORF cDNA clone expression plasmid - HG13755-UT from Sino Biological Species Human

Human UNC5C Gene ORF cDNA clone expression plasmid, C-His tag - HG13755-CH from Sino Biological Species Human

Human UNC5C Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13755-ACG from Sino Biological Species Human

Human UNC5C Gene ORF cDNA clone expression plasmid, N-HA tag - HG13755-NY from Sino Biological Species Human

Human UNC5C Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13755-ACR from Sino Biological Species Human

Human UNC5C ORF Clone (BC041156) - CDCS411430 from Creative biogene Species Human Accession O95185

Human UNC5C ORF clone (BC041156) - CDCB159726 from Creative biogene Species Human

Human UNC5H3 (NP_003719) VersaClone cDNA - RDC1768 from R&D Systems Prices $499.00 Sizes 10 µg Species Human

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