UNC5C

Gene Symbol	UNC5C
Entrez Gene	8633
Alt Symbol	UNC5H3
Species	Human
Gene Type	protein-coding
Description	unc-5 homolog C (C. elegans)
Other Description	netrin receptor UNC5C|protein unc-5 homolog 3|protein unc-5 homolog C|unc-5 homolog 3|unc5 (C.elegans homolog) c
Swissprots	Q8IUT0 O95185
Accessions	AAY41022 EAX06061 EAX06062 O95185 AF055634 AAC67491 AK022487 AK290500 BAF83189 AK308421 BC034747 BC041156 AAH41156 BX538341 XM_005263321 XP_005263378 NM_003728 NP_003719
Function	Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity). {ECO:0000250}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Mainly expressed in brain. Also expressed in kidney. Not expressed in developing or adult lung. {ECO:0000269|PubMed:9782087}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human UNC5C protein fragment - ab160125 from Abcam Category Protein Source Wheat germ Species Human

UNC5H3 / UNC5C Antibody Blocking Peptide - LS-E16625 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UNC5H3 / UNC5C Antibody Blocking Peptide - LS-E23424 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UNC5H3 / UNC5C Antibody Blocking Peptide - LS-E8547 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UNC5H3 / UNC5C Antibody Blocking Peptide - LS-E27013 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human UNC5H3/UNC5C Protein - H00008633-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

UNC5C-Antibody-Center-Blocking-Peptide - BP6919c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

UNC5C blocking peptide - GTX47544-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog

Recombinant Human UNC5H3 Fc Chimera, CF - 1005-UN-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

UNC5C Blocking Peptide - 33R-10004 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

UNC5C Blocking Peptide - 33R-9901 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

UNC5C Peptide - AC21-1838-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

UNC5C - H00008633-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

UNC5C - H00008633-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

UNC5C Peptide - 42-092P from ProSci Category Peptide Species Human, Mouse

UNC5C fusion protein - Ag16243 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human UNC5C, GST-tagged - UNC5C-3599H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human UNC5C, Fc Chimera - UNC5C-1072H from Creative Biomart Category Protein Source NSO Cells Species Human

Recombinant Human Netrin receptor UNC5C(UNC5C) - CSB-YP025630HU CSB-EP025630HU CSB-BP025630HU CSB-MP025630HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human UNC5H3 Fc Chimera Protein, CF - 1005-UN from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Human UNC5H3 (Ala40 - Asp376) Accession # O95185 IEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus Species Human

UNC5C Peptide - abx165020 from Abbexa Category Peptide Species Human, Mouse, Rat

UNC5C - TP324257 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

UNC5C , Peptide - MBS426110 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Dog

UNC5H3/UNC5C Recombinant Protein Antigen - NBP1-86476PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

UNC5C-Blocking-Peptide-N-term - BP19910a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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