GPNMB

Gene Symbol	GPNMB
Entrez Gene	10457
Alt Symbol	HGFIN, NMB
Species	Human
Gene Type	protein-coding
Description	glycoprotein (transmembrane) nmb
Other Description	glycoprotein NMB|glycoprotein nmb-like protein|osteoactivin|transmembrane glycoprotein HGFIN|transmembrane glycoprotein NMB
Swissprots	A4D155 Q6UVX1 Q8N1A1 Q14956
Accessions	AAN59897 AAP22336 AAP22337 EAL24259 EAW93781 EAW93782 EAW93783 EAW93784 Q14956 AF322909 AAG42839 AI952217 AJ505015 CAD43718 AK292078 BAF84767 AK296779 BAG59357 AK297031 BAG59559 AK297051 BAG59577 AK297055 BAG59580 AK297803 BAG60141 AK303071 BAG64187 AK304671 BAG65446 AK312279 BAG35208 AY359124 AAQ89481 BC011595 AAH11595 BC025297 BC032783 AAH32783 BM750843 BT007074 AAP35737 BU537639 CD105306 DQ892084 ABM83010 DQ895277 ABM86203 X76534 CAA54044 XM_005249578 XP_005249635 NM_001005340 NP_001005340 NM_002510 NP_002501
Function	Could be a melanogenic enzyme. {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Detected at the cell surface in different types of cancers cells, including glioblastoma multiforme cells and most melanoma cell lines.
Tissue Specificity	Up-regulated in various cancer cells, including in glioblastoma multiforme. Expressed in many melanoma cells, as well as in tissue macrophages, including liver Kuppfer cells and lung alveolar macrophages, in podocytes and in some cells of the ciliary body of the eye (at protein level). Hardly detectable in healthy brain. {ECO:0000269|PubMed:16489096, ECO:0000269|PubMed:16609006, ECO:0000269|PubMed:7814155}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Osteoactivin Human ELISA Kit - ab193711 from Abcam Category ELISA Kit Prices $475.00 Sizes 1 x 96 tests Sensitivity 45 pg/ml Range 45 pg/ml - 12000 pg/ml

Human GPNMB / Osteoactivin ELISA Kit (Sandwich ELISA) - LS-F2915 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 49.16-12000 pg/ml

Mouse GPNMB / Osteoactivin ELISA Kit (Sandwich ELISA) - LS-F2982 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 49.16-12000 pg/ml

Human GPNMB / Osteoactivin ELISA Kit (Sandwich ELISA) - LS-F173 from LifeSpan Bioscience Category ELISA Kit Prices $520.00, $930.00, $2,140.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 49.16 pg/ml Range 49.16-12000 pg/ml

Mouse GPNMB / Osteoactivin ELISA Kit (Sandwich ELISA) - LS-F11563 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 49.16-12000 pg/ml

Human GPNMB / Transmembrane Glycoprotein NMB ELISA Kit - RAB0718 from Sigma-Aldrich Category ELISA Kit Prices $633.00 Sizes 1 kt

Human Osteoactivin/GPNMB DuoSet ELISA - DY2550 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 125.00 - 8,000 pg/mL

Mouse Osteoactivin/GPNMB DuoSet ELISA - DY2330 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 0.312 - 20 ng/mL

Human GPNMB ELISA Kit - abx056180 from Abbexa Category ELISA Kit

Neuromedin B (NMB), Human, ELISA Kit - CEA803Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 56.8pg/mL Range 123.5-10,000pg/mL

Neuromedin B (NMB), Human, ELISA Kit - E01N0549 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Transmembrane glycoprotein NMB (GPNMB), Human, ELISA Kit - CSB-EL009727HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Transmembrane glycoprotein NMB, GPNMB, Human, ELISA Kit - E2770h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Human Osteoactivin ELISA - ELH-Osteoactivin from RayBiotech Category ELISA Kit Prices $462.00, $832.00, $1,850.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 45 pg/ml Range 45 pg/ml - 12,000 pg/ml

glycoprotein (transmembrane) nmb, ELISA Kit - MBS933647 from MyBioSource Category ELISA Kit Prices $250.00, $860.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Osteoactivin ELISA KIT - DEIA7058 from Creative Diagnostics Category ELISA Kit Sensitivity 62.5 pg/mL Range 125-8000 pg/mL

GPNMB, ELISA Kit - MBS825048 from MyBioSource Category ELISA Kit Prices $470.00 Sizes 96 tests Sensitivity 10 pg/ml Range 156 pg/ml - 10000 pg/ml

GPNMB/Osteoactivin, ELISA Kit - MBS177336 from MyBioSource Category ELISA Kit Prices $425.00 Sizes 1x96 wells Sensitivity < 10pg/ml Range 156pg/ml-10,000pg/ml

Human GPNMB ELISA Kit - CEK1181 from Cohesion Biosciences Category ELISA Kit Prices $360.00 Sizes 96 t Sensitivity 10 pg/ml Range 156 pg/ml - 10000 pg/ml

Human GPNMB/Osteoactivin PicoKine™ ELISA Kit EK1251 - EK1251 from Boster Bio Category ELISA Kit Prices $369.00 Sizes 1 kit Sensitivity <10pg/ml Range 156pg/ml-10,000pg/ml *This assay range is determined using common samples. For samples with low target protein concentrations, users can adjust the standard curve to extend the lower limit of assay range.

Human Transmembrane glycoprotein NMB(GPNMB) ELISA kit - CSB-EL009727HU from Cusabio Category ELISA Kit Sensitivity 0.195 ng/ml Range 0.78 ng/ml-50 ng/ml

Rat GPNMB / Osteoactivin ELISA Kit (Custom ELISA) - LS-F19791 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 49.16-12000 pg/ml

Human GPNMB / Osteoactivin ELISA Kit (Custom ELISA) - LS-F19792 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 49.16-12000 pg/ml

Osteoactivin / GPNMB - ABE-719-01 from Nordic BioSite Sensitivity 46 pg/mL Range 93.75-6000 pg/mL

Human Transmembrane glycoprotein NMB ELISA Kit - abx250837 from Abbexa Category ELISA Kit

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