GPNMB

Gene Symbol	GPNMB
Entrez Gene	10457
Alt Symbol	HGFIN, NMB
Species	Human
Gene Type	protein-coding
Description	glycoprotein (transmembrane) nmb
Other Description	glycoprotein NMB|glycoprotein nmb-like protein|osteoactivin|transmembrane glycoprotein HGFIN|transmembrane glycoprotein NMB
Swissprots	A4D155 Q6UVX1 Q8N1A1 Q14956
Accessions	AAN59897 AAP22336 AAP22337 EAL24259 EAW93781 EAW93782 EAW93783 EAW93784 Q14956 AF322909 AAG42839 AI952217 AJ505015 CAD43718 AK292078 BAF84767 AK296779 BAG59357 AK297031 BAG59559 AK297051 BAG59577 AK297055 BAG59580 AK297803 BAG60141 AK303071 BAG64187 AK304671 BAG65446 AK312279 BAG35208 AY359124 AAQ89481 BC011595 AAH11595 BC025297 BC032783 AAH32783 BM750843 BT007074 AAP35737 BU537639 CD105306 DQ892084 ABM83010 DQ895277 ABM86203 X76534 CAA54044 XM_005249578 XP_005249635 NM_001005340 NP_001005340 NM_002510 NP_002501
Function	Could be a melanogenic enzyme. {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Detected at the cell surface in different types of cancers cells, including glioblastoma multiforme cells and most melanoma cell lines.
Tissue Specificity	Up-regulated in various cancer cells, including in glioblastoma multiforme. Expressed in many melanoma cells, as well as in tissue macrophages, including liver Kuppfer cells and lung alveolar macrophages, in podocytes and in some cells of the ciliary body of the eye (at protein level). Hardly detectable in healthy brain. {ECO:0000269|PubMed:16489096, ECO:0000269|PubMed:16609006, ECO:0000269|PubMed:7814155}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NMB Gene - orb91802 from Biorbyt Prices $366.00 Sizes 10 μg Species Human

Human NMB Gene cDNA Clone - orb144455 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-GPNMB-cDNA-Clone - DC03134 from Abgent, a WuXi AppTec company Prices $772.20 Sizes 10 µg Species Human Accession BC032783

GPNMB - MBS1268526 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC011595

GPNMB - MBS1272204 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC032783

Human GPNMB cDNA clone(NM_001005340.1) - CDFH007857 from Creative Biomart Species Human Accession NM_001005340.1

Human GPNMB cDNA clone(NM_002510.2) - CDFH007858 from Creative Biomart Species Human Accession NM_002510.2

Human GPNMB ORF clone(NM_002510.2) - CDCL184455 from Creative Biomart Species Human Accession NM_002510.2

Human GPNMB ORF Clone(NM_002510.2) - CDCL165112 from Creative Biomart Species Human Accession NM_002510.2

Human GPNMB ORF Clone(NM_001005340.1) - CDCL165113 from Creative Biomart Species Human Accession NM_001005340.1

Human GPNMB ORF Clone(NM_002510.2) - CDCR283259 from Creative Biomart Species Human Accession NM_002510.2

Human GPNMB ORF Clone(NM_002510.2) - CDCR283260 from Creative Biomart Species Human Accession NM_002510.2

Human GPNMB ORF Clone(NM_001005340.1) - CDCR339666 from Creative Biomart Species Human Accession NM_001005340.1

Human GPNMB ORF Clone(NM_001005340.1) - CDCR339667 from Creative Biomart Species Human Accession NM_001005340.1

Human GPNMB/Osteoactivin transcript variant 2 Gene ORF cDNA clone in cloning vector - HG11305-M from Sino Biological Species Human

Human GPNMB/Osteoactivin transcript variant 2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11305-ACG from Sino Biological Species Human

Human GPNMB/Osteoactivin transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11305-NF from Sino Biological Species Human

Human GPNMB/Osteoactivin transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11305-NM from Sino Biological Species Human

Human GPNMB/Osteoactivin transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11305-CF from Sino Biological Species Human

Human GPNMB/Osteoactivin transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11305-CM from Sino Biological Species Human

Human GPNMB/Osteoactivin transcript variant 2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11305-NY from Sino Biological Species Human

Human GPNMB transcript variant 2 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG11305-M-F from Sino Biological Species Human Accession NM_002510.2

Human GPNMB/Osteoactivin transcript variant 2 Gene ORF cDNA clone expression plasmid, C-His tag - HG11305-CH from Sino Biological Species Human

Human GPNMB/Osteoactivin transcript variant 2 Gene ORF cDNA clone expression plasmid - HG11305-UT from Sino Biological Species Human

Human GPNMB/Osteoactivin transcript variant 2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11305-ACR from Sino Biological Species Human

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